Dear Editor, The French nun Sister André who is believed to be the world's second-oldest
person was celebrating her 117th birthday on February 11, 2021 after having a SARS-CoV …

The SARS-CoV-2 infection determines the COVID-19 syndrome characterized, in the worst
cases, by severe respiratory distress, pulmonary and cardiac fibrosis, inflammatory cytokine …

Objectives Since the 1980s, life expectancy at birth (e 0) in the United States has fallen
steadily behind that of other high-income countries, widening the US e 0 disadvantage. We …

Age is a major risk factor for severe coronavirus disease-2019 (COVID-19). Here, we
interrogate the transcriptional features and cellular landscape of the aging human lung. By …

Abstract SARS-CoV-2 virus, the causative agent of the coronavirus infectious disease-19
(COVID-19), is taking the globe by storm, approaching 500,000 confirmed cases and over …

We examine the cellular and soluble determinants of coronavirus disease 2019 (COVID-19)
relative to aging by performing mass cytometry in parallel with clinical blood testing and …

Introduction Increased age has been reported to be a factor for COVID-19 severe outcomes.
However, many studies do not consider the age dependency of comorbidities, which …

This paper examines why a larger share of COVID-19 deaths occurs among young and
middle-aged adults in developing countries than in high-income countries. Using novel data …

The COVID-19 pandemic triggered an unprecedented rise in mortality that translated into life
expectancy losses around the world, with only a few exceptions. We estimate life expectancy …

A poor socioeconomic environment and social adversity are fundamental determinants of
human life span, well-being and health. Previous influenza pandemics showed that …