Many insect cells are encapsulated within the exoskeleton and cannot be dissociated intact,
making them inaccessible to single-cell transcriptomic profiling. We have used single …

Single-cell techniques are a promising way to unravel the complexity and heterogeneity of
transcripts at the cellular level and to reveal the composition of different cell types and …

Background Recent technological advances opened the opportunity to simultaneously study
gene expression for thousands of individual cells on a genome-wide scale. The …

Single-cell RNA sequencing (scRNAseq) experiments provide a powerful means to identify
clusters of cells that share common gene expression signatures. A major challenge in …

Gene expression profiles are typically described at the level of the tissue or, often in
Drosophila, at the level of the whole organism. Collapsing the gene expression of entire …

Single‐cell RNA sequencing (scRNA‐seq) has emerged as a powerful tool for investigating
cell states and functions at the single‐cell level. It has greatly revolutionized transcriptomic …

Drosophila provides a powerful genetic system and an excellent model to study the
development and function of the nervous system. The fly's small brain and complex behavior …

With the advent of single-cell RNA sequencing (scRNA-seq) technologies, there has been a
spike in studies involving scRNA-seq of several tissues across diverse species including …

Single‐cell RNA sequencing provides a new approach to an old problem: how to study
cellular diversity in complex biological systems. This powerful tool has been instrumental in …

Long-read sequencing is driving rapid progress in genome assembly across all major
groups of life, including species of the family Drosophilidae, a longtime model system for …