Background There remains a dearth of life-course studies analyzing childhood environment
and late-life chronic illness. In particular, few have addressed possible early-life predictors of …

Stress exposure and stress reactivity may be potent factors associated with increased risk of
dementia. The 2017 Lancet Commission on Dementia and its 2020 update reviewed …

Objectives High rates of dementia have been observed in Aboriginal Australians. This study
aimed to describe childhood stress in older Aboriginal Australians and to examine …

Objectives This study examined the relationship between childhood adversities and major
depression in older adults over 8 years. Methods The study sample consisted of 16 946 …

Objectives: We evaluated whether the effects of recent stressful life events (SLEs) and early
childhood adversities (ECAs) on depressive symptoms are consistent between men and …

Background: Posttraumatic stress disorder is associated with increased dementia risk but
less is known about stress because of everyday problems in diverse populations. Methods …

Importance The prevalence of dementia in Japan has been increasing. Childhood poverty
has been associated with increased risk of cognitive impairment, possibly mediated by …

Background Psychological stress is recognized as a major risk factor for a range of non-
communicable diseases and possibly mortality. The extent to which the type and timing of …

Background: It has been estimated that one third of dementia cases may be preventable
through modifiable lifestyle interventions. Epidemiological evidence suggests a link between …

Objective Childhood adversities have been associated with adulthood depressiveness, but
the contribution of adult risk factors is seldom described. We examined whether adult risk …