Using circulating tumor DNA in colorectal cancer: current and evolving practices

M Malla, JM Loree, PM Kasi, AR Parikh - Journal of Clinical Oncology, 2022 - ascopubs.org
There exists a tremendous opportunity in identifying and determining the appropriate
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …

Circulating tumor DNA detection: A potential tool for colorectal cancer management

H Li, C Jing, J Wu, J Ni, H Sha, X Xu… - Oncology …, 2019 - spandidos-publications.com
Colorectal cancer (CRC) is frequently diagnosed at an advanced stage of the disease, the
pathogenesis of which is influenced by genetic and epigenetic events. Circulating tumor …

[HTML][HTML] Circulating tumour DNA as a biomarker in resectable and irresectable stage IV colorectal cancer; a systematic review and meta-analysis

RP Jones, SA Pugh, J Graham, JN Primrose… - European Journal of …, 2021 - Elsevier
Background For patients with metastatic colorectal cancer, stratification for treatment
(surgery or chemotherapy) is often based on crude clinicopathological characteristics like …

Circulating tumor DNA in precision oncology and its applications in colorectal cancer

MF Arisi, E Dotan, SV Fernandez - International Journal of Molecular …, 2022 - mdpi.com
Circulating tumor DNA (ctDNA) is a component of cell-free DNA (cfDNA) that is shed by
malignant tumors into the bloodstream and other bodily fluids. ctDNA can comprise up to …

Clinical application of circulating tumour DNA in colorectal cancer

M Loft, YH To, P Gibbs, J Tie - The Lancet Gastroenterology & …, 2023 - thelancet.com
Liquid biopsies that detect circulating tumour DNA (ctDNA) have the potential to
revolutionise the personalised management of colorectal cancer. For patients with early …

Circulating tumor DNA is a prognostic marker of tumor recurrence in stage II and III colorectal cancer: multicentric, prospective cohort study (ALGECOLS)

L Benhaim, O Bouché, C Normand, A Didelot… - European Journal of …, 2021 - Elsevier
Background In non-metastatic colorectal cancer (CRC), we evaluated prospectively the
pertinence of longitudinal detection and quantification of circulating tumor DNA (ctDNA) as a …

The use of circulating tumor DNA to monitor and predict response to treatment in colorectal cancer

M Reece, H Saluja, P Hollington, CS Karapetis… - Frontiers in …, 2019 - frontiersin.org
Background: Colorectal cancer is one of the most common cancers worldwide and has a
high mortality rate following disease recurrence. Treatment efficacy is maximized by …

The promise of circulating tumor DNA (ctDNA) in the management of early-stage colon cancer: a critical review

S Chakrabarti, H Xie, R Urrutia, A Mahipal - Cancers, 2020 - mdpi.com
Simple Summary Currently, the treatment for localized colon cancer consists of surgery and,
if the presence of residual cancer cells is suspected, chemotherapy following the surgery …

Prognostic value of circulating tumor DNA in patients with colon cancer: Systematic review

G Fan, K Zhang, X Yang, J Ding, Z Wang, J Li - PloS one, 2017 - journals.plos.org
The application of circulating tumor DNA (ctDNA) represents a non-invasive method for
tumor detection. Its prognostic significance in patients with colorectal cancer is controversial …

Tumor-informed or tumor-agnostic circulating tumor DNA as a biomarker for risk of recurrence in resected colorectal cancer patients

HT Chan, S Nagayama, M Otaki, YM Chin… - Frontiers in …, 2023 - frontiersin.org
Introduction Circulating tumor DNA (ctDNA) has been increasingly recognized as a
promising minimally-invasive biomarker that could identify patients with minimal residual …