KP Kepp - Progress in neurobiology, 2016 - Elsevier
Alzheimer's Disease (AD) is a highly complex disease involving a broad range of clinical, cellular, and biochemical manifestations that are currently not understood in combination …
KH Tse, K Herrup - Journal of neurochemistry, 2017 - Wiley Online Library
Many have criticized the amyloid cascade hypothesis of Alzheimer's disease for its inconsistencies and failures to either accurately predict disease symptoms or guide the …
RS Madnani - Frontiers in Neurology, 2023 - frontiersin.org
Alzheimer's disease (AD), the most common form of dementia, is a striking example of the connection between neurophysiological abnormalities and higher-order cognitive …
Dementia, a prevalent condition among older individuals, has profound societal implications. Extensive research has resulted in no cure for what is perceived as the most …
O Sheppard, M Coleman - Exon Publications, 2020 - exonpublications.com
Alzheimer's disease is the most common form of dementia and the most common neurodegenerative disease. It manifests as a decline in short-term memory and cognition …
DJ Selkoe - Neurologic clinics, 2000 - neurologic.theclinics.com
Few experiences in the work of a neurologic diagnostician are more disquieting than informing both patient and family that the diagnosis is Alzheimer's disease (AD). Yet, with the …
The global prevalence of dementia is estimated to be as high as 24 million, and is predicted to double every 20 years through to 2040, leading to a costly burden of disease. Alzheimer …
P Dourlen, D Kilinc, N Malmanche, J Chapuis… - Acta …, 2019 - Springer
Abstract A strong genetic predisposition (60–80% of attributable risk) is present in Alzheimer's disease (AD). In view of this major genetic component, identification of the …