The global prevalence of dementia is as high as 24 million, and has been predicted to
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …

Alzheimer's Disease (AD) is a highly complex disease involving a broad range of clinical,
cellular, and biochemical manifestations that are currently not understood in combination …

Many have criticized the amyloid cascade hypothesis of Alzheimer's disease for its
inconsistencies and failures to either accurately predict disease symptoms or guide the …

Alzheimer's disease (AD), the most common form of dementia, is a striking example of the
connection between neurophysiological abnormalities and higher-order cognitive …

Dementia, a prevalent condition among older individuals, has profound societal
implications. Extensive research has resulted in no cure for what is perceived as the most …

Alzheimer's disease is the most common form of dementia and the most common
neurodegenerative disease. It manifests as a decline in short-term memory and cognition …

Few experiences in the work of a neurologic diagnostician are more disquieting than
informing both patient and family that the diagnosis is Alzheimer's disease (AD). Yet, with the …

Deciphering Alzheimer Disease Cold Spring Harbor Perspectives in Medicine Skip to main
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The global prevalence of dementia is estimated to be as high as 24 million, and is predicted
to double every 20 years through to 2040, leading to a costly burden of disease. Alzheimer …

Abstract A strong genetic predisposition (60–80% of attributable risk) is present in
Alzheimer's disease (AD). In view of this major genetic component, identification of the …