Alzheimer's disease (AD) is considered to have a large genetic component. Our knowledge
of this component has progressed over the last 10 years, thanks notably to the advent of …

The current conceptualization of Alzheimer disease (AD) is driven by the amyloid
hypothesis, in which a deterministic chain of events leads from amyloid deposition and then …

Introduction: Alzheimer's disease (AD) is the most common cause of dementia globally and
imposes a growing burden on healthcare systems. Historical background: Alois Alzheimer …

The field of Alzheimer's disease (AD) research has grown exponentially over the past few
decades, especially since the isolation and identification of amyloid-β from postmortem …

Clinical trial results presented in 2019 suggest that antibody-based removal of cerebral
amyloid β (Aβ) plaques may possibly clear tau tangles and modestly slow cognitive decline …

Alzheimer's disease (AD) is a prevalent neurodegenerative disease characterized by both
amnestic and non-amnestic clinical manifestations. It accounts for approximately 60-70% of …

As the most common dementia, Alzheimer's disease (AD) exacts an immense personal,
societal, and economic toll. AD was first described at the neuropathological level in the early …

More than 100 years after description of Alzheimer's disease (AD), two major pathological
processes observed already by Alois Alzheimer, remain as the main explanation of the …

Current pathogenic theories for Alzheimer disease (AD) and aging favor the notion that
lesions and their constituent proteins are the initiators of disease due to toxicity. Whether this …

Alzheimer's disease (AD) was first described a little more than 100 years ago. It is the most
common cause of dementia with an estimated prevalence of 30 million people worldwide, a …