ChAMP: updated methylation analysis pipeline for Illumina BeadChips
Abstract Summary The Illumina Infinium HumanMethylationEPIC BeadChip is the new
platform for high-throughput DNA methylation analysis, effectively doubling the coverage …
platform for high-throughput DNA methylation analysis, effectively doubling the coverage …
[HTML][HTML] Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
Background High-throughput profiling of DNA methylation status of CpG islands is crucial to
understand the epigenetic regulation of genes. The microarray-based Infinium methylation …
understand the epigenetic regulation of genes. The microarray-based Infinium methylation …
[HTML][HTML] RnBeads 2.0: comprehensive analysis of DNA methylation data
DNA methylation is a widely investigated epigenetic mark with important roles in
development and disease. High-throughput assays enable genome-scale DNA methylation …
development and disease. High-throughput assays enable genome-scale DNA methylation …
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
DNA methylation is the most studied epigenetic mark and CpG methylation is central to
many biological processes and human diseases. Since cancer has highlighted the …
many biological processes and human diseases. Since cancer has highlighted the …
[HTML][HTML] Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates
Two-thirds of gene promoters in mammals are associated with regions of non-methylated
DNA, called CpG islands (CGIs), which counteract the repressive effects of DNA methylation …
DNA, called CpG islands (CGIs), which counteract the repressive effects of DNA methylation …
[HTML][HTML] A cross-package Bioconductor workflow for analysing methylation array data
Methylation in the human genome is known to be associated with development and disease.
The Illumina Infinium methylation arrays are by far the most common way to interrogate …
The Illumina Infinium methylation arrays are by far the most common way to interrogate …
Genome-wide detection of cytosine methylation by single molecule real-time sequencing
5-Methylcytosine (5mC) is an important type of epigenetic modification. Bisulfite sequencing
(BS-seq) has limitations, such as severe DNA degradation. Using single molecule real-time …
(BS-seq) has limitations, such as severe DNA degradation. Using single molecule real-time …
[HTML][HTML] Single-cell DNA methylome and 3D multi-omic atlas of the adult mouse brain
Cytosine DNA methylation is essential in brain development and is implicated in various
neurological disorders. Understanding DNA methylation diversity across the entire brain in a …
neurological disorders. Understanding DNA methylation diversity across the entire brain in a …
Base resolution methylome profiling: considerations in platform selection, data preprocessing and analysis
Bisulfite treatment-based methylation microarray (mainly Illumina 450K Infinium array) and
next-generation sequencing (reduced representation bisulfite sequencing, Agilent …
next-generation sequencing (reduced representation bisulfite sequencing, Agilent …
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
DNA methylation plays key roles in diverse biological processes such as X chromosome
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …