Salivary gland function and aging: a model for studying the interaction of aging and systemic disease

BJ Baum, JA Ship, AJ Wu - Critical Reviews in Oral Biology …, 1992 - journals.sagepub.com
This review describes an approach to examining the interaction of aging and systemic
disease on a key aspect of oral physiology, salivation. The approach requires several steps …

Structure and function in aging human salivary glands

J Scott - Gerodontology, 1986 - Wiley Online Library
Degenerative structural changes develop in the secretory tissues of most salivary glands in
man with advancing age. Quantitative studies have shown losses of a third or more in the …

Salivary glands and the aging process: mechanistic aspects, health-status and medicinal-efficacy monitoring

RM Nagler - Biogerontology, 2004 - Springer
Xerostomia is a major complaint of many elderly individuals, and although they seek
medical help, it usually provides no adequate relief. This complaint is considered a major …

Oral Defenses and Disease: Salivary Gland Function 1

ID Mandel - Gerodontology, 1984 - Wiley Online Library
Recent studies on parotid gland flow rate and composition in healthy subjects do not support
the conventional wisdom that there is a gradual deterioration in salivary gland function with …

Aging and saliva: a review of the literature

A Vissink, FKL Spijkervet… - Special Care in …, 1996 - Wiley Online Library
It is often assumed that salivary secretion reduces with age. About 25% of the elderly suffer
from oral dry‐ness and related complaints. Nevertheless, data on stimulated salivary flow …

Age-related changes in unstimulated salivary function and composition and its relations to medications and oral sensorial complaints

RM Nagler, O Hershkovich - Aging clinical and experimental research, 2005 - Springer
Background and aims: The purpose of the current study was to examine the salivary flow
rate and composition in relation to drug consumption and idiopathic oral sensorial …

Impact of aging on human salivary gland function: a community-based study

CK Yeh, DA Johnson, MWJ Dodds - Aging Clinical and Experimental …, 1998 - Springer
A comprehensive evaluation of salivary flow rates and composition was undertaken in an
age-and community-stratified population. A nonmedicated subpopulation was used to …

Cross-sectional and longitudinal analyses of stimulated parotid salivary constituents in healthy, different-aged subjects

AJ Wu, JC Atkinson, PC Fox, BJ Baum… - Journal of …, 1993 - academic.oup.com
Background. Salivary gland dysfunction has traditionally been associated with old age, and
complaints of xerostomia are common in an elderly population. Measurement of certain …

Longitudinal analysis of parotid and submandibular salivary flow rates in healthy, different-aged adults

JA Ship, NE Nolan, SA Puckett - The Journals of Gerontology …, 1995 - academic.oup.com
Background. Early studies suggested that salivary gland dysfunction was a normal sequela
of aging. Recent research on healthy, different-aged adults has led to a revision of these …

Aging and salivary cytokine concentrations as predictors of whole saliva flow rates among women: a preliminary study

C Streckfus, L Bigler, T O'Bryan - Gerontology, 2002 - karger.com
Introduction: How aging influences the secretion of saliva is not entirely clear. Postmortem
studies have demonstrated that, with age, the parenchyma of the salivary glands is gradually …