Background Understanding the molecular basis of susceptibility factors to the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global health imperative. It …

SARS-CoV-2 infection can cause an inflammatory syndrome (COVID-19) leading, in many
cases, to bilateral pneumonia, severe dyspnea, and in~ 5% of these, death. DNA …

Background Epigenetic alterations upon microbial challenge have been described as both a
defence strategy and a result of pathogenic manipulation. While most COVID-19 studies …

In the early 2000s, emerging SARS‐CoV‐2, which is highly pathogenic, posed a great threat
to public health. During COVID‐19, epigenetic regulation is deemed to be an important part …

Male sex and advanced age are associated with severe symptoms of COVID-19. Sex and
age also exhibit substantial associations with genome-wide DNA methylation (DNAm) …

The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence
suggest that severe COVID-19 is associated with durable scars to the epigenome …

Single-cell transcriptome studies have revealed immune dysfunction in COVID-19 patients,
including lymphopenia, T cell exhaustion, and increased levels of pro-inflammatory …

Background There are no prior reports that compare differentially methylated regions of DNA
in blood samples from COVID-19 patients to samples collected before the SARS-CoV-2 …

Background Patients infected with the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide …

To integrate gene expression and DNA methylation data and find the potential role of DNA
methylation in the invasion and replication of severe acute respiratory syndrome coronavirus …