For centuries, people believed that bats possessed sinister powers. Bats are thought to be
ancestral hosts to many deadly viruses affecting humans including Ebola, rabies, and most …

Inflammatory molecules evolved partly to protect hosts from viruses, but increasing evidence
suggests that they cause disease pathology and chronic conditions, and play a role in aging …

A majority of viruses that have caused recent epidemics with high lethality rates in people,
are zoonoses originating from wildlife. Among them are filoviruses (eg, Marburg, Ebola) …

There have been several major outbreaks of emerging viral diseases, including Hendra,
Nipah, Marburg and Ebola virus diseases, severe acute respiratory syndrome (SARS) and …

In recent years, viruses similar to those that cause serious disease in humans and other
mammals have been detected in apparently healthy bats. These include filoviruses …

Bats live longer than similar-sized mammals, but the number of lineages that have
independently evolved extreme longevity has not previously been determined. Here we …

Bats have emerged as unique mammalian vectors harboring a diverse range of highly lethal
zoonotic viruses with minimal clinical disease. Despite having sustained complete genomic …

Bats are special in their ability to live long and host many emerging viruses. Our previous
studies showed that bats have altered inflammasomes, which are central players in aging …

The ongoing West African Ebola epidemic highlights a recurring trend in the zoonotic
emergence of virulent pathogens likely to come from bat reservoirs that has caused …

Bats are the longest-lived mammals, given their body size. However, the underlying
molecular mechanisms of their extended healthspans are poorly understood. To address …