An overview of viral mutagenesis and the impact on pathogenesis of SARS-CoV-2 variants

MZI Khan, A Nazli, H Al-Furas, MI Asad, I Ajmal… - Frontiers in …, 2022 - frontiersin.org
Viruses are submicroscopic, obligate intracellular parasites that carry either DNA or RNA as
their genome, protected by a capsid. Viruses are genetic entities that propagate by using the …

COVID-19 and SARS-CoV-2 variants: current challenges and health concern

M Zeyaullah, AM AlShahrani, K Muzammil… - Frontiers in …, 2021 - frontiersin.org
The ongoing coronavirus disease 2019 (COVID-19) outbreak in Wuhan, China, was
triggered and unfolded quickly throughout the globe by severe acute respiratory syndrome …

SARS-CoV-2 mutations and their viral variants

B Cosar, ZY Karagulleoglu, S Unal, AT Ince… - Cytokine & growth factor …, 2022 - Elsevier
Mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occur
spontaneously during replication. Thousands of mutations have accumulated and continue …

Emerging SARS-CoV-2 variants: genetic variability and clinical implications

A Dubey, S Choudhary, P Kumar, S Tomar - Current microbiology, 2022 - Springer
The sudden rise in COVID-19 cases in 2020 and the incessant emergence of fast-spreading
variants have created an alarming situation worldwide. Besides the continuous …

[HTML][HTML] Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions

AI Abulsoud, HM El-Husseiny, AA El-Husseiny… - Biomedicine & …, 2023 - Elsevier
COVID-19 is a worldwide pandemic caused by SARS-coronavirus-2 (SARS-CoV-2). Less
than a year after the emergence of the Covid-19 pandemic, many vaccines have arrived on …

Mutations in SARS-CoV-2; Consequences in structure, function, and pathogenicity of the virus

B Bakhshandeh, Z Jahanafrooz, A Abbasi, MB Goli… - Microbial …, 2021 - Elsevier
The third pandemic of coronavirus infection, called COVID-19 disease, began recently in
China. The newly discovered coronavirus, entitled SARS-CoV-2, is the seventh member of …

SARS-CoV-2: an overview of the genetic profile and vaccine effectiveness of the five variants of concern

R Dumache, A Enache, I Macasoi, CA Dehelean… - Pathogens, 2022 - mdpi.com
With the onset of the COVID-19 pandemic, enormous efforts have been made to understand
the genus SARS-CoV-2. Due to the high rate of global transmission, mutations in the viral …

SARS‐CoV‐2 variants and vulnerability at the global level

VP Chavda, AB Patel… - Journal of medical …, 2022 - Wiley Online Library
Numerous variants of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
pandemic have evolved. Viral variants may evolve with harmful susceptibility to the immunity …

Epidemiology and characteristics of SARS-CoV-2 variants of concern: the impacts of the spike mutations

T Cocherie, K Zafilaza, V Leducq, S Marot, V Calvez… - Microorganisms, 2022 - mdpi.com
SARS-CoV-2 expresses on its surface the Spike protein responsible for binding with the
ACE2 receptor and which carries the majority of immunodominant epitopes. Mutations …

A global analysis of conservative and non-conservative mutations in SARS-CoV-2 detected in the first year of the COVID-19 world-wide diffusion

N Balasco, G Damaggio, L Esposito, F Villani… - Scientific Reports, 2021 - nature.com
The ability of SARS-CoV-2 to rapidly mutate represents a remarkable complicancy.
Quantitative evaluations of the effects that these mutations have on the virus …