Association of cellular immunity with severity of COVID-19 from the perspective of antigen-specific memory T cell responses and cross-reactivity

S Fujii, S Yamasaki, T Iyoda, K Shimizu - Inflammation and Regeneration, 2022 - Springer
Coronaviruses regularly cause outbreaks of zoonotic diseases characterized by severe
pneumonia. The new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS …

Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?

SJ Kent, DS Khoury, A Reynaldi, JA Juno… - Nature Reviews …, 2022 - nature.com
The rapid development of multiple vaccines providing strong protection from severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a major achievement …

Adaptive immune responses and immunity to SARS-CoV-2

D Primorac, K Vrdoljak, P Brlek, E Pavelić… - Frontiers in …, 2022 - frontiersin.org
Since the onset of the COVID-19 pandemic, the medical field has been forced to apply the
basic knowledge of immunology with the most up-to-date SARS-CoV-2 findings and …

Immune memory in mild COVID-19 patients and unexposed donors reveals persistent T cell responses after SARS-CoV-2 infection

A Ansari, R Arya, S Sachan, SN Jha, A Kalia… - Frontiers in …, 2021 - frontiersin.org
Understanding the causes of the diverse outcome of COVID-19 pandemic in different
geographical locations is important for the worldwide vaccine implementation and pandemic …

The Influence of Cross-Reactive T Cells in COVID-19

PJ Eggenhuizen, JD Ooi - Biomedicines, 2024 - mdpi.com
Memory T cells form from the adaptive immune response to historic infections or
vaccinations. Some memory T cells have the potential to recognise unrelated pathogens like …

COVID-19 patients display distinct SARS-CoV-2 specific T-cell responses according to disease severity

M Kroemer, L Spehner, L Vettoretti, A Bouard… - Journal of Infection, 2021 - Elsevier
Adaptive Immune responses generated by SARS-CoV-2 virus in convalescent patients
according to disease severity remain poorly characterized. To this end, we designed a …

[HTML][HTML] Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity

CR Moderbacher, SI Ramirez, JM Dan, A Grifoni… - Cell, 2020 - cell.com
Limited knowledge is available on the relationship between antigen-specific immune
responses and COVID-19 disease severity. We completed a combined examination of all …

Protective immunity after COVID-19 has been questioned: What can we do without SARS-CoV-2-IgG detection?

JG Melgaço, T Azamor, APDA Bom - 2020 - arca.fiocruz.br
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces a severe acute
respiratory syndrome that is called COVID-19. Clinical manifestations of COVID-19 include …

Cell‐mediated and humoral adaptive immune responses to SARS‐CoV‐2 are lower in asymptomatic than symptomatic COVID‐19 patients

A Mazzoni, L Maggi, M Capone… - European Journal of …, 2020 - Wiley Online Library
The characterization of cell‐mediated and humoral adaptive immune responses to SARS‐
CoV‐2 is fundamental to understand COVID‐19 progression and the development of …

SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection

DM Altmann, RJ Boyton - Science immunology, 2020 - science.org
In efforts to synthesize a clear understanding of SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) protective immunity, antibody analysis has been paralleled by T …