Immunosenescence contributes to a decreased capacity of the immune system to respond
effectively to infections or vaccines in the elderly. The full extent of the biological changes …

Understanding why we age and how that process can be delayed or reversed are topics that
have engaged both researchers and the general public [1]. From a scientific perspective …

Vaccines are a highly effective intervention for conferring protection against infections and
reducing the associated morbidity and mortality in vaccinated individuals. However, ageing …

People with advanced age have a higher susceptibility to infections and exhibit increased
mortality and morbidity as the ability of the immune system to combat infections decreases …

Owing to its memory and plasticity, the immune system (IS) is capable of recording all the
immunological experiences and stimuli it was exposed to. The combination of type, dose …

With increasing age, the human immune system undergoes characteristic changes, termed
immunosenescence, which lead to increased incidence and severity of infectious diseases …

The world's population is aging, which brings about huge scientific challenges. Since the
biological process of aging is by far the greatest risk factor for most chronic diseases …

The progressive increase of the aged population worldwide mandates new strategies to
ensure sustained health and well-being with age. The development of better and/or new …

One of the most profound public health consequences of immune senescence is reflected in
an increased susceptibility to influenza and other acute respiratory illnesses, as well as a …

Immunosenescence is a process associated with aging that leads to dysregulation of cells of
innate and adaptive immunity, which may become dysfunctional. Consequently, older adults …