CPC1, the principal regulatory protein required for cross-pathway control of amino acid
biosynthetic genes in Neurospora crassa, contains a domain similar to the DNA-binding …

CPC1 is the transcriptional activator of amino acid biosynthetic genes of Neurospora crassa.
CPC1 function in vivo was abolished upon deletion of segments of cpc-1 corresponding to …

The levels of transcripts for Neurospora crassa genes concerned with cellular and metabolic
functions changed dramatically at different stages of asexual development. Transcripts for …

The arg-12 locus of Neurospora crassa encodes ornithine carbamoyl transferase, which is
one of many amino acid synthetic enzymes whose activity is regulated through cross …

Abstract cpc-1 is the locus specifying what is believed to be the major trans-activating
transcription factor that regulates expression of amino acid biosynthetic genes subject to …

In Neurospora crassa starvation for single amino acids leads to derepression of enzymes in
many amino acid synthetic pathways. Regulation occurs at the level of transcription via …

Expression of the gene cpc-1 is required for cross-pathway-mediated regulation of amino
acid-biosynthetic genes in Neurospora crassa. We have cloned cpc-1 and present an …

Phenotypic and molecular studies of the mutation U142 indicate that the cpc-2+ gene is
required to activate general amino acid control under conditions of amino acid limitation in …

The effects of amino acid limitation on gene expression have been investigated in
Neurospora crassa strains carrying normal (cpc-1+) or mutant (cpc-1) alleles at a locus …

Based on characteristic amino acid sequences of kinases that phosphorylate the α subunit
of eukaryotic translation initiation factor 2 (eIF2α kinases), degenerate oligonucleotide …