Introduction Aberrant DNA methylation frequently occurs in the inflammatory mucosa in
ulcerative colitis (UC) and is involved in UC-related tumorigenesis. We performed …

The cause of inflammatory bowel disease (IBD) is still unknown, but there is growing
evidence that environmental factors such as epigenetic changes can contribute to the …

Background Although DNA methylation of colonic mucosa in ulcerative colitis (UC) has been
suggested, the majority of published reports indicate the correlation between methylation of …

DNA methylation has been implied to play a role in the immune dysfunction associated with
inflammatory bowel disease (IBD) and the disease development of ulcerative colitis (UC) …

Abstract Background and Aims The aim of this study was to investigate the genome-wide
DNA methylation status in treatment-naïve ulcerative colitis [UC], and to explore the …

Patients with long-standing ulcerative colitis (UC) have higher risk of developing colorectal
cancer. Albeit the causes remain to be understood, epigenetic alterations have been …

Background DNA methylation constitutes a key epigenetic mechanism by which cells
regulate gene transcription. Among its roles are the dynamic regulation of gene expression …

Background: Ulcerative colitis (UC) is an idiopathic disease of the large intestine with
evidence pointing to the role of epigenetic changes. Methods: Searches were performed in …

BACKGROUND: DNA methylation is considered one of the epigenetic mechanisms believed
to play a role in the pathogenesis of ulcerative colitis (UC). The aim of this study was to …

Background: Evidence points to the role of DNA methylation in ulcerative colitis (UC)-
associated cancer (UCC), the most serious complication of ulcerative colitis. A better …