Innate and adaptive immune responses to SARS-CoV-2 in humans: relevance to acquired immunity and vaccine responses

SC Jordan - Clinical & Experimental Immunology, 2021 - academic.oup.com
The factors responsible for the spectrum of coronavirus 19 (COVID-19) disease severity and
the genesis and nature of protective immunity against COVID-19 remain elusive. Multiple …

Adaptive immune responses and immunity to SARS-CoV-2

D Primorac, K Vrdoljak, P Brlek, E Pavelić… - Frontiers in …, 2022 - frontiersin.org
Since the onset of the COVID-19 pandemic, the medical field has been forced to apply the
basic knowledge of immunology with the most up-to-date SARS-CoV-2 findings and …

[HTML][HTML] Adaptive immunity to SARS-CoV-2 and COVID-19

A Sette, S Crotty - Cell, 2021 - cell.com
The adaptive immune system is important for control of most viral infections. The three
fundamental components of the adaptive immune system are B cells (the source of …

[HTML][HTML] Immunology of COVID-19: current state of the science

N Vabret, GJ Britton, C Gruber, S Hegde, J Kim… - Immunity, 2020 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting …

Longitudinal dynamics of SARS-CoV-2-specific cellular and humoral immunity after natural infection or BNT162b2 vaccination

P Almendro-Vázquez, R Laguna-Goya… - PLoS …, 2021 - journals.plos.org
The timing of the development of specific adaptive immunity after natural SARS-CoV-2
infection, and its relevance in clinical outcome, has not been characterized in depth …

Cellular and humoral immune responses in covid-19 and immunotherapeutic approaches

A Hasan, E Al-Ozairi, Z Al-Baqsumi… - ImmunoTargets and …, 2021 - Taylor & Francis
Abstract Coronavirus disease 2019 (Covid-19), caused by the novel coronavirus severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), can range in severity from …

[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–Current perspectives

JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
SARS-CoV-2 is a new beta coronavirus, similar to SARS-CoV-1, that emerged at the end of
2019 in the Hubei province of China. It is responsible for coronavirus disease 2019 (COVID …

Potential SARS-CoV-2 immune correlates of protection in infection and vaccine immunization

Y Sui, Y Bekele, JA Berzofsky - Pathogens, 2021 - mdpi.com
Both SARS-CoV-2 infections and vaccines induce robust immune responses. Current data
suggested that high neutralizing antibody titers with sustained Th1 responses might …

Cell‐mediated and humoral adaptive immune responses to SARS‐CoV‐2 are lower in asymptomatic than symptomatic COVID‐19 patients

A Mazzoni, L Maggi, M Capone… - European Journal of …, 2020 - Wiley Online Library
The characterization of cell‐mediated and humoral adaptive immune responses to SARS‐
CoV‐2 is fundamental to understand COVID‐19 progression and the development of …

[HTML][HTML] Dynamic SARS-CoV-2-specific B-cell and T-cell responses following immunization with an inactivated COVID-19 vaccine

Y Chen, S Yin, X Tong, Y Tao, J Ni, J Pan, M Li… - Clinical Microbiology …, 2022 - Elsevier
Objective The dynamic adaptive immune responses elicited by the inactivated virus vaccine
CoronaVac remain elusive. Methods In a prospective cohort of 100 healthcare professionals …