Cumulative SARS-CoV-2 mutations and corresponding changes in immunity in an immunocompromised patient indicate viral evolution within the host

ST Sonnleitner, M Prelog, S Sonnleitner… - Nature …, 2022 - nature.com
Different scenarios explaining the emergence of novel variants of concern (VOC) of the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported …

The variants question: What is the problem?

D Zella, M Giovanetti, F Benedetti… - Journal of medical …, 2021 - Wiley Online Library
The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) originated in Wuhan,
China in early December 2019 has rapidly widespread worldwide. Over the course of the …

The COVID-19 pandemic: viral variants and vaccine efficacy

M Ciotti, M Ciccozzi, M Pieri… - Critical reviews in clinical …, 2022 - Taylor & Francis
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
prompted the scientific community and the pharmaceutical companies to put maximum …

The development of SARS-CoV-2 variants: the gene makes the disease

R Perez-Gomez - Journal of developmental biology, 2021 - mdpi.com
A novel coronavirus (SARS-CoV-2) emerged towards the end of 2019 that caused a severe
respiratory disease in humans called COVID-19. It led to a pandemic with a high rate of …

COVID-19 vaccines: their effectiveness against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its emerging variants

R Noor, S Shareen, M Billah - Bulletin of the National Research Centre, 2022 - Springer
Background The world has been suffering from the COVID-19 pandemic (officially declared
by WHO in March 2020), caused by the severe acute respiratory β-coronavirus 2 (SARS …

SARS‐CoV‐2 biology and variants: anticipation of viral evolution and what needs to be done

R Luo, A Delaunay‐Moisan, K Timmis… - Environmental …, 2021 - Wiley Online Library
The global propagation of SARS‐CoV‐2 and the detection of a large number of variants,
some of which have replaced the original clade to become dominant, underscores the fact …

Biochemical features and mutations of key proteins in SARS-CoV-2 and their impacts on RNA therapeutics

L Zeng, D Li, W Tong, T Shi, B Ning - Biochemical pharmacology, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic. Three viral proteins, the spike protein (S) for attachment of virus to host cells, 3 …

Large-scale analysis of SARS-CoV-2 spike-glycoprotein mutants demonstrates the need for continuous screening of virus isolates

B Schrörs, P Riesgo-Ferreiro, P Sorn, R Gudimella… - PLoS …, 2021 - journals.plos.org
Due to the widespread of the COVID-19 pandemic, the SARS-CoV-2 genome is evolving in
diverse human populations. Several studies already reported different strains and an …

Molecular evolutionary characteristics of SARS‐CoV‐2 emerging in the United States

S Wang, X Xu, C Wei, S Li, J Zhao… - Journal of medical …, 2022 - Wiley Online Library
SARS‐CoV‐2 is a newly discovered beta coronavirus at the end of 2019, which is highly
pathogenic and poses a serious threat to human health. In this paper, 1875 SARS‐CoV‐2 …

[HTML][HTML] Different mutations in SARS-CoV-2 associate with severe and mild outcome

Á Nagy, S Pongor, B Győrffy - International journal of antimicrobial agents, 2021 - Elsevier
Introduction Genomic alterations in a viral genome can lead to either better or worse
outcome and identifying these mutations is of utmost importance. Here, we correlated …