Colorectal cancer (CRC) is one of the most common and deadliest cancers worldwide.
Patient survival can be greatly improved if cancerous lesions are detected early. 1 Despite a …

Background There is an increasing demand for accurate biomarkers for early non-invasive
colorectal cancer detection. We employed a genome-scale marker discovery method to …

Colorectal cancer (CRC) is the third most common cause of cancer-related death in the
United States. Early identification and treatment of pre-cancerous colorectal lesions, or node …

Background Colorectal cancer is the fourth cause of cancer-related deaths worldwide,
though detection at early stages associates with good prognosis. Thus, there is a clear …

Background Colorectal polyp is known a precursor of colorectal cancer (CRC) that holds an
increased risk for progression to CRC. Circulating cell-free DNA (cfDNA) methylation has …

Importance Detection of molecular residual disease and risk stratification as early as
possible may improve the treatment of patients with cancer. Efficient pragmatic tests are …

Background Current noninvasive assays have limitations in the early detection of colorectal
cancer. We evaluated the clinical utility of promoter methylation of the long noncoding RNA …

Aberrant DNA methylation has shown promise as a biomarker for the early detection of
cancer. To discover novel genes frequently methylated at an early stage in colorectal cancer …

Screening for early‐stage disease is vital for reducing colorectal cancer (CRC)‐related
mortality. Methylation of circulating tumor DNA has been previously used for various types of …

Colorectal cancer (CRC) develops through the accumulation of both genetic and epigenetic
alterations. However, while the former are already used as prognostic and predictive …