Severe COVID-19 is associated with molecular signatures of aging in the human brain

M Mavrikaki, JD Lee, IH Solomon, FJ Slack - Nature Aging, 2022 - nature.com
Abstract As coronavirus disease 2019 (COVID-19) and aging are both accompanied by
cognitive decline, we hypothesized that COVID-19 might lead to molecular signatures …

COVID-19 and Alzheimer's disease: How one crisis worsens the other

X Xia, Y Wang, J Zheng - Translational Neurodegeneration, 2021 - Springer
Alzheimer's disease (AD) has emerged as a key comorbidity of coronavirus disease 2019
(COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …

One-year trajectory of cognitive changes in older survivors of COVID-19 in Wuhan, China: a longitudinal cohort study

YH Liu, Y Chen, QH Wang, LR Wang, L Jiang… - JAMA …, 2022 - jamanetwork.com
Importance Determining the long-term impact of COVID-19 on cognition is important to
inform immediate steps in COVID-19 research and health policy. Objective To investigate …

Post-infection cognitive impairments in a cohort of elderly patients with COVID-19

YH Liu, YR Wang, QH Wang, Y Chen, X Chen… - Molecular …, 2021 - Springer
Background Understanding the long-term effects of coronavirus disease 2019 (COVID-19)
on cognitive function is essential for monitoring the cognitive decline in the elderly …

[HTML][HTML] COVCOG 2: cognitive and memory deficits in long COVID: a second publication from the COVID and cognition study

P Guo, A Benito Ballesteros, SP Yeung… - Frontiers in aging …, 2022 - frontiersin.org
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has
been often characterized as a respiratory disease. However, it is increasingly being …

Long-term effects of SARS-CoV-2 infection on human brain and memory

Q Ding, HJ Zhao - Cell Death Discovery, 2023 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have caused
several waves of outbreaks. From the ancestral strain to Omicron variant, SARS-CoV-2 has …

Alzheimer's and Parkinson's diseases predict different COVID-19 outcomes: a UK Biobank study

Y Yu, M Travaglio, R Popovic, NS Leal, LM Martins - Geriatrics, 2021 - mdpi.com
In December 2019, a coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), began infecting humans, causing a novel disease, coronavirus disease 19 (COVID …

Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment

Y Zhou, J Xu, Y Hou, JB Leverenz, A Kallianpur… - Alzheimer's research & …, 2021 - Springer
Background Dementia-like cognitive impairment is an increasingly reported complication of
SARS-CoV-2 infection. However, the underlying mechanisms responsible for this …

Accelerated biological aging in COVID-19 patients

X Cao, W Li, T Wang, D Ran, V Davalos… - Nature …, 2022 - nature.com
Chronological age is a risk factor for SARS-CoV-2 infection and severe COVID-19. Previous
findings indicate that epigenetic age could be altered in viral infection. However, the …

SARS-CoV-2 infection increases the gene expression profile for Alzheimer's disease risk

R Green, K Mayilsamy, AR McGill, TE Martinez… - … Therapy-Methods & …, 2022 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic has caused over 600,000,000
infections globally thus far. Up to 30% of individuals with mild to severe disease develop …