Genome‑wide association studies (GWASs) have revealed numerous loci associated with
Parkinson's disease (PD). However, some potential causal/risk genes were still not revealed …

Background: Parkinson's disease (PD) is the second most frequent neurodegenerative
disease worldwide. Clinical diagnosis can only be made when the vast majority of the …

Neuroinflammation is one of the most significant factors involved in the initiation and
progression of Parkinson's disease. PD is a neurodegenerative disorder with a motor …

Background The dysfunction of immune system and inflammation contribute to the
Parkinson's disease (PD) pathogenesis. Cytokines, oxidative stress, neurotoxin and …

Background Copper ions are essential for cellular physiology. Cuproptosis is a novel
method of copper-dependent cell death, and the cuproptosis-based signature for glioma …

Objective We aimed to identify key susceptibility gene targets in multiple datasets generated
from postmortem brains and blood of Parkinson's disease (PD) patients and healthy controls …

Background Cuproptosis is considered a novel copper‐dependent cell death model. In this
study, we established a novel scoring system based on 10 cuproptosis‐related genes …

Parkinson's disease (PD) is a slowly progressive geriatric disease, which can be one of the
leading causes of serious socioeconomic burden in the aging society. Clinical trials suggest …

Background Motor symptoms are well-characterized in Parkinson's disease (PD). However,
non-motor symptoms, such as depression, are commonly observed and can appear up to 10 …

Parkinson's disease (PD) is referring to the multi-systemic α-synucleinopathy with Lewy
bodies deposited in midbrain. In ageing, the environmental and genetic factors work …