Patho-physiology of aging and immune-senescence: possible correlates with comorbidity and mortality in middle-aged and old COVID-19 patients

S Farheen, S Agrawal, S Zubair, A Agrawal… - Frontiers in …, 2021 - frontiersin.org
During the last 2 years, the entire world has been severely devastated by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic (COVID-19) as it resulted in …

[HTML][HTML] An account of immune senescence in the clinical pathophysiology of COVID-19 infection in aging

S Jain, E Abrham, MN Khan, R Mathur - Aging and disease, 2021 - ncbi.nlm.nih.gov
Worldwide COVID-19 infection poses an enormous risk to public health and an alarming
global socioeconomic burden. The impact of the COVID-19 pandemic on individuals with …

Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?

V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …

Remodeling of the immune response with aging: immunosenescence and its potential impact on COVID-19 immune response

LL Cunha, SF Perazzio, J Azzi, P Cravedi… - Frontiers in …, 2020 - frontiersin.org
Elderly individuals are the most susceptible to an aggressive form of coronavirus disease
(COVID-19), caused by SARS-CoV-2. The remodeling of immune response that is observed …

Aging, inflammaging and immunosenescence as risk factors of severe COVID-19

AM Tizazu, HM Mengist, G Demeke - Immunity & Ageing, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …

Risk factors for long COVID in older adults

Y Hu, Y Liu, H Zheng, L Liu - Biomedicines, 2023 - mdpi.com
As time has passed following the COVID-19 pandemic, individuals infected with SARS-CoV-
2 have gradually exhibited a variety of symptoms associated with long COVID in the …

I mmunosenescence and inflammaging: risk factors of severe COVID-19 in older people

AJ Pietrobon, FME Teixeira, MN Sato - Frontiers in immunology, 2020 - frontiersin.org
Old individuals are more susceptible to various infections due to immunological changes
that occur during the aging process. These changes named collectively as …

SARS-CoV-2, COVID-19 and the aging immune system

JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …

Role of senescence and aging in SARS-CoV-2 infection and COVID-19 disease

SM Lynch, G Guo, DS Gibson, AJ Bjourson, TS Rai - Cells, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has resulted in a global pandemic associated with substantial …

Triple jeopardy in ageing: COVID-19, co-morbidities and inflamm-ageing

IM Rea, HD Alexander - Ageing research reviews, 2022 - Elsevier
Covid-19 endangers lives, has disrupted normal life, changed the way medicine is practised
and is likely to alter our world for the foreseeable future. Almost two years on since the …