A TGF‐β signaling‐related lncRNA signature for prediction of glioma prognosis, immune microenvironment, and immunotherapy response

WW Duan, LT Yang, J Liu, ZY Dai… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims The dysregulation of TGF‐β signaling is a crucial pathophysiological process in
tumorigenesis and progression. LncRNAs have diverse biological functions and are …

An immune gene-related five-lncRNA signature for to predict glioma prognosis

X Wang, M Gao, J Ye, Q Jiang, Q Yang, C Zhang… - Frontiers in …, 2020 - frontiersin.org
Background The tumor immune microenvironment is closely related to the malignant
progression and treatment resistance of glioma. Long non-coding RNA (lncRNA) plays a …

A novel inflammatory lncRNAs prognostic signature for predicting the prognosis of low-grade glioma patients

Z Xiang, X Chen, Q Lv, X Peng - Frontiers in Genetics, 2021 - frontiersin.org
Background As immunotherapy has received attention as new treatments for brain cancer,
the role of inflammation in the process of glioma is of particular importance. Increasing …

A five immune-related lncRNA signature as a prognostic target for glioblastoma

X Li, L Sun, X Wang, N Wang, K Xu… - Frontiers in molecular …, 2021 - frontiersin.org
Background: A variety of regulatory approaches including immune modulation have been
explored as approaches to either eradicate antitumor response or induce suppressive …

An immune-related lncRNA signature to predict survival in glioma patients

P Xia, Q Li, G Wu, Y Huang - Cellular and molecular neurobiology, 2021 - Springer
Glioma is the most common and fatal primary brain tumor in human. Long non-coding RNA
(lncRNA), which are characterized by regulation of gene expression and chromatin …

[HTML][HTML] Construction of lncRNA-mediated ceRNA network to reveal clinically relevant lncRNA biomarkers in glioblastomas

XY Zan, L Li - Oncology letters, 2019 - spandidos-publications.com
Cross-talk between competing endogenous RNAs (ceRNAs) play key roles in tumor
development. In this study, we performed exon-level expression profiling on 26 …

Development of an immune-related LncRNA prognostic signature for glioma

Y Cao, H Zhu, J Tan, W Yin, Q Zhou, Z Xin, Z Wu… - Frontiers in …, 2021 - frontiersin.org
Introduction Glioma is the most common primary cancer of the central nervous system with
dismal prognosis. Long noncoding RNAs (lncRNAs) have been discovered to play key roles …

Identification of immune-related lncRNA prognostic signature and molecular subtypes for glioblastoma

W Yu, Y Ma, W Hou, F Wang, W Cheng, F Qiu… - Frontiers in …, 2021 - frontiersin.org
Background Glioblastoma multiforme (GBM) is extensively genetically and transcriptionally
heterogeneous, which poses challenges for classification and management. Long …

Comprehensive analysis of oxidative stress-related lncRNA signatures in glioma reveals the discrepancy of prognostic and immune infiltration

Z Shi, Y Wu, Q Zhuo, Y Zuo, J Lin, H Shi, H Zhou… - Scientific Reports, 2023 - nature.com
Oxidative stress refers to the process of reactive oxide species (ROS) increase in human
body due to various factors, which leads to oxidative damage in human tissues. Current …

Identification of an epithelial-mesenchymal transition-related lncRNA prognostic signature for patients with glioblastoma

XJ Yang, S Niu, JQ Liu, J Fang, ZY Wu, S Ling, GF Di… - Scientific Reports, 2021 - nature.com
Glioblastoma (GBM) is a strikingly heterogeneous and lethal brain tumor with very poor
prognosis. LncRNAs play critical roles in the tumorigenesis of GBM through regulation of …