[HTML][HTML] Role of genetic variants and gene expression in the susceptibility and severity of COVID-19

S Choudhary, K Sreenivasulu, P Mitra… - Annals of laboratory …, 2021 - synapse.koreamed.org
Since its first report in December 2019, coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly emerged as a …

Investigating the ACE2 polymorphisms in COVID‐19 susceptibility: An in silico analysis

N Pouladi, S Abdolahi - Molecular genetics & genomic …, 2021 - Wiley Online Library
Abstract Background Novel coronavirus (SARS‐CoV‐2) became an epidemic disease and
lead to a pneumonia outbreak first in December 2019 in Wuhan, China. The symptoms …

The impact of ACE2 polymorphisms on COVID-19 disease: susceptibility, severity, and therapy

F Chen, Y Zhang, X Li, W Li, X Liu… - Frontiers in Cellular and …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has currently spread worldwide, leading to high morbidity and …

Human genetic basis of coronavirus disease 2019

H Deng, X Yan, L Yuan - Signal transduction and targeted therapy, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) caused by a novel coronavirus, severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in considerable …

SARS-CoV-2 infections and COVID-19 mortalities strongly correlate with ACE1 I/D genotype

N Yamamoto, Y Ariumi, N Nishida, R Yamamoto… - Gene, 2020 - Elsevier
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). The relentless spread and pathogenicity of the virus have …

SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease

N Alimoradi, M Sharqi, D Firouzabadi, MM Sadeghi… - Virology Journal, 2022 - Springer
COVID-19 and the renin-angiotensin system (RAS) are linked by angiotensin-converting
enzyme 2 (ACE2), a key enzyme in RAS that has been validated as a SARS-CoV-2 receptor …

Genetic susceptibility of COVID-19: a systematic review of current evidence

SA SeyedAlinaghi, M Mehrtak, M MohsseniPour… - European Journal of …, 2021 - Springer
Introduction While COVID-19 pandemic continues to spread worldwide, researchers have
linked patterns of traits to poor disease outcomes. Risk factors for COVID-19 include asthma …

ACE2 polymorphisms as potential players in COVID-19 outcome

AS Khayat, PP de Assumpção, BC Meireles Khayat… - PLoS …, 2020 - journals.plos.org
The clinical condition COVID-19, caused by SARS-CoV-2, was declared a pandemic by the
WHO in March 2020. Currently, there are more than 5 million cases worldwide, and the …

ACE and ACE2 Gene Variants Are Associated With Severe Outcomes of COVID-19 in Men

LE Martinez-Gomez, B Herrera-Lopez… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
current coronavirus disease 2019 (COVID-19) pandemic, affecting more than 219 countries …

Variants in ACE2; potential influences on virus infection and COVID-19 severity

B Bakhshandeh, SG Sorboni, AR Javanmard… - Infection, Genetics and …, 2021 - Elsevier
The third pandemic of coronavirus infection, called COVID-19 disease, was first detected in
November 2019th. Various determinants of disease progression such as age, sex, virus …