Systemic markers of inflammation and cognitive decline in old age

MT Schram, SM Euser, AJM De Craen… - Journal of the …, 2007 - Wiley Online Library
OBJECTIVES: To investigate whether higher circulating levels of C‐reactive protein (CRP),
interleukin‐6 (IL‐6), and α1‐antichymotrypsin (ACT) are associated with worse cognitive …

Inflammation and rate of cognitive change in high-functioning older adults

DE Alley, EM Crimmins, A Karlamangla… - The Journals of …, 2008 - academic.oup.com
Background. Inflammatory proteins including interleukin-6 (IL-6) and C-reactive protein
(CRP) have been associated with incident cognitive impairment, but little research has …

Inflammatory markers and cognitive function in middle-aged adults: the Whitehall II study

D Gimeno, MG Marmot, A Singh-Manoux - Psychoneuroendocrinology, 2008 - Elsevier
OBJECTIVES: To assess whether C-reactive protein (CRP) and interleukin-6 (IL-6) are
associated with low cognitive performance and decline in middle-aged adults …

The association between systemic inflammation and cognitive performance in the elderly: the Sydney Memory and Ageing Study

JN Trollor, E Smith, E Agars, SA Kuan, BT Baune… - Age, 2012 - Springer
Inflammation may contribute to cognitive decline and dementia. This study examined the
cross-sectional relationships between markers of systemic inflammation (C-reactive protein …

The inflammatory markers CRP, IL-6, and IL-10 are associated with cognitive function—data from the Berlin Aging Study II

C Tegeler, JL O'Sullivan, N Bucholtz, D Goldeck… - Neurobiology of …, 2016 - Elsevier
Inflammation may be an underlying mechanism in cognitive decline. The present study
investigated the relationship between cognitive function and the inflammatory markers C …

Serum inflammatory proteins and cognitive decline in older persons

MG Dik, C Jonker, CE Hack, JH Smit, HC Comijs… - Neurology, 2005 - AAN Enterprises
Objective: To assess whether serum levels of the inflammatory proteins α1-antichymotrypsin
(ACT), C-reactive protein (CRP), interleukin-6 (IL-6), and albumin are associated with …

The cross-sectional and longitudinal associations between IL-6, IL-10, and TNFα and cognitive outcomes in the Mayo Clinic Study of Aging

AMV Wennberg, CE Hagen… - The Journals of …, 2019 - academic.oup.com
Background Chronic inflammation has been linked with geriatric-related conditions,
including dementia. Inflammatory cytokine levels, including interleukin (IL)-6, IL-10, and …

Long-term assessment of inflammation and healthy aging in late life: the Cardiovascular Health Study All Stars

NS Jenny, B French, AM Arnold… - … Series A: Biomedical …, 2012 - academic.oup.com
Background. Associations of inflammation with age-related pathologies are documented;
however, it is not understood how changes in inflammation over time impact healthy aging …

Association of inflammation and cognition in the elderly: a systematic review and meta-analysis

S Leonardo, F Fregni - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Background The development of mild cognitive impairment (MCI) and Alzheimer's disease
(AD) may be associated with an inflammatory process. Inflammatory cytokines may be a …

Midlife C-reactive protein and risk of cognitive decline: a 31-year follow-up

D Laurin, JD Curb, KH Masaki, LR White… - Neurobiology of …, 2009 - Elsevier
There is evidence for a relationship between raised inflammatory markers, including high
sensitivity C-reactive protein (hs-CRP), measured late in life, and an increased risk of …