Hippocampal sclerosis of aging is a key Alzheimer's disease mimic: clinical-pathologic correlations and comparisons with both alzheimer's disease and non …
WD Brenowitz, SE Monsell, FA Schmitt… - Journal of …, 2014 - content.iospress.com
Hippocampal sclerosis of aging (HS-Aging) neuropathology was observed in more than
15% of aged individuals in prior studies. However, much remains unknown about the clinical …
15% of aged individuals in prior studies. However, much remains unknown about the clinical …
Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease
Hippocampal sclerosis of aging (HS-Aging) is a causative factor in a large proportion of
elderly dementia cases. The current definition of HS-Aging rests on pathologic criteria …
elderly dementia cases. The current definition of HS-Aging rests on pathologic criteria …
Characterization of hippocampal sclerosis of aging and its association with other neuropathologic changes and cognitive deficits in the oldest-old
Hippocampal sclerosis of aging (HS-A) is a common age-related neuropathological lesion
characterized by neuronal loss and astrogliosis in subiculum and CA1 subfield of …
characterized by neuronal loss and astrogliosis in subiculum and CA1 subfield of …
Hippocampal sclerosis of aging can be segmental: two cases and review of the literature
ET Ighodaro, GA Jicha, FA Schmitt… - … of Neuropathology & …, 2015 - academic.oup.com
Hippocampal sclerosis of aging (HS-Aging) is a neurodegenerative disease that mimics
Alzheimer disease (AD) clinically and has a prevalence rivaling AD in advanced age …
Alzheimer disease (AD) clinically and has a prevalence rivaling AD in advanced age …
Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: Combined data from 13 community-based or population …
Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-
NC) and Alzheimer's disease neuropathologic change (ADNC) are each associated with …
NC) and Alzheimer's disease neuropathologic change (ADNC) are each associated with …
Hippocampal sclerosis in advanced age: clinical and pathological features
Hippocampal sclerosis is a relatively common neuropathological finding (∼ 10% of
individuals over the age of 85 years) characterized by cell loss and gliosis in the …
individuals over the age of 85 years) characterized by cell loss and gliosis in the …
Hippocampal sclerosis in tau-negative frontotemporal lobar degeneration
KA Josephs, DW Dickson - Neurobiology of aging, 2007 - Elsevier
Tau-negative frontotemporal lobar degeneration (FTLD) can be divided into those with motor
neuron disease (FTLD-MND), and those without MND, but with ubiquitin-immunoreactive …
neuron disease (FTLD-MND), and those without MND, but with ubiquitin-immunoreactive …
Hippocampal sclerosis and TDP‐43 pathology in aging and A lzheimer disease
Objective To investigate the association of hippocampal sclerosis (HS) with TAR‐DNA
binding protein of 43kDa (TDP‐43) and other common age‐related pathologies, dementia …
binding protein of 43kDa (TDP‐43) and other common age‐related pathologies, dementia …
Relative neuron loss in hippocampal sclerosis of aging and Alzheimer's disease
R Ihara, BD Vincent, MR Baxter, EE Franklin… - Annals of …, 2018 - Wiley Online Library
Objective To characterize the pattern of neuron loss in hippocampal sclerosis of aging (HS‐
Aging) and age‐related diseases and to evaluate its contribution to cognitive impairment in …
Aging) and age‐related diseases and to evaluate its contribution to cognitive impairment in …
In severe ADNC, hippocampi with comorbid LATE-NC and hippocampal sclerosis have substantially more astrocytosis than those with LATE-NC or hippocampal …
DM Niedowicz, Y Katsumata… - … of Neuropathology & …, 2023 - academic.oup.com
Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-
NC) and hippocampal sclerosis of aging (HS-A) pathologies are found together at autopsy …
NC) and hippocampal sclerosis of aging (HS-A) pathologies are found together at autopsy …