Immune profiling of Parkinson's disease revealed its association with a subset of infiltrating cells and signature genes

X Zhang, Z Shao, S Xu, Q Liu, C Liu, Y Luo… - Frontiers in Aging …, 2021 - frontiersin.org
Parkinson's disease (PD) is an age-related and second most common neurodegenerative
disorder. In recent years, increasing evidence revealed that peripheral immune cells might …

Significant difference of immune cell fractions and their correlations with differential expression genes in Parkinson's disease

Y Huang, H Liu, J Hu, C Han, Z Zhong… - Frontiers in Aging …, 2021 - frontiersin.org
Parkinson's disease (PD) is the second most neurodegenerative disease in the world. T cell
infiltration in the central nervous system (CNS) has provided insights that the peripheral …

Identification of immune-related hub genes in Parkinson's disease

L Chen, Y Wang, J Huang, B Hu, W Huang - Frontiers in Genetics, 2022 - frontiersin.org
Background: Parkinson's disease (PD) is a common, age-related, and progressive
neurodegenerative disease. Growing evidence indicates that immune dysfunction plays an …

Novel diagnostic biomarkers related to immune infiltration in Parkinson's disease by bioinformatics analysis

P Zhang, L Zhao, H Li, J Shen, H Li… - Frontiers in Neuroscience, 2023 - frontiersin.org
Background Parkinson's disease (PD) is Pengfei Zhang Liwen Zhao Pengfei Zhang Liwen
Zhao a common neurological disorder involving a complex relationship with immune …

Identification and validation of key molecules associated with humoral immune modulation in Parkinson's disease based on bioinformatics

N Xing, Z Dong, Q Wu, P Kan, Y Han, X Cheng… - Frontiers in …, 2022 - frontiersin.org
Objective Parkinson's disease (PD) is the most common neurodegenerative movement
disorder and immune-mediated mechanism is considered to be crucial to pathogenesis …

Identification of potential immune-related hub genes in Parkinson's disease based on machine learning and development and validation of a diagnostic classification …

G Xin, J Niu, Q Tian, Y Fu, L Chen, T Yi, K Tian, X Sun… - PloS One, 2023 - journals.plos.org
Background Parkinson's disease is the second most common neurodegenerative disease in
the world. However, current diagnostic methods are still limited, and available treatments …

[HTML][HTML] Integrative analysis of potential biomarkers and immune cell infiltration in Parkinson's disease

X Chen, W Cao, Y Zhuang, S Chen, X Li - Brain Research Bulletin, 2021 - Elsevier
Background Parkinson's disease (PD) is a common neurodegenerative disease in the
elderly population. However, there are no reliable diagnostic biomarkers for PD, and the …

Specific immune status in Parkinson's disease at different ages of onset

J Tian, SB Dai, SS Jiang, WY Yang, YQ Yan… - npj Parkinson's …, 2022 - nature.com
Recent evidence suggests that innate and adaptive immunity play a crucial role in
Parkinson's disease (PD). However, studies regarding specific immune cell classification in …

The role of immune dysfunction in Parkinson's disease Development

D Cossu, T Hatano, N Hattori - International Journal of Molecular …, 2023 - mdpi.com
Recent research has unveiled intriguing insights suggesting that the body's immune system
may be implicated in Parkinson's disease (PD) development. Studies have observed …

Causal role of immune cells on risk of Parkinson's disease: a Mendelian randomization study

J Gu, Y Qiao, S Cong - Frontiers in Aging Neuroscience, 2024 - frontiersin.org
Background Previous observational studies have suggested a correlation between immune
cells and Parkinson's disease (PD), yet specific investigations into the causal relationship …