Molecular mechanisms of environmental exposures and human disease

H Wu, CM Eckhardt, AA Baccarelli - Nature reviews genetics, 2023 - nature.com
A substantial proportion of disease risk for common complex disorders is attributable to
environmental exposures and pollutants. An appreciation of how environmental pollutants …

Environmental exposures and gene regulation in disease etiology

TM Edwards, JP Myers - Environmental health perspectives, 2007 - ehp.niehs.nih.gov
Objective Health or disease is shaped for all individuals by interactions between their genes
and environment. Exactly how the environment changes gene expression and how this can …

Environmental chemical exposures and human epigenetics

L Hou, X Zhang, D Wang… - International journal of …, 2012 - academic.oup.com
Every year more than 13 million deaths worldwide are due to environmental pollutants, and
approximately 24% of diseases are caused by environmental exposures that might be …

Epigenomics in environmental health

BC Christensen, CJ Marsit - Frontiers in genetics, 2011 - frontiersin.org
This review considers the emerging relationships between environmental factors and
epigenetic alterations and the application of genome-wide assessments to better define …

Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships

VK Cortessis, DC Thomas, AJ Levine, CV Breton… - Human genetics, 2012 - Springer
Abstract Changes in epigenetic marks such as DNA methylation and histone acetylation are
associated with a broad range of disease traits, including cancer, asthma, metabolic …

Environmental epigenetics and its implication on disease risk and health outcomes

SM Ho, A Johnson, P Tarapore, V Janakiram… - ILAR …, 2012 - academic.oup.com
This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …

[HTML][HTML] Effects of Environmental Factors and Epigenetic on Health and the Development of Diseases

M Farrokhi, F Taheri, E Karami, R Khorram… - Kindle, 2023 - preferpub.org
The effects of environmental factors and epigenetics on health and disease development
are complex and interconnected. Environmental factors encompass external influences like …

The role of environmental exposures and the epigenome in health and disease

BPU Perera, C Faulk, LK Svoboda… - Environmental and …, 2020 - Wiley Online Library
The genetic material of every organism exists within the context of regulatory networks that
govern gene expression, collectively called the epigenome. Epigenetics has taken center …

Hallmarks of environmental insults

A Peters, TS Nawrot, AA Baccarelli - Cell, 2021 - cell.com
Environmental insults impair human health around the world. Contaminated air, water, soil,
food, and occupational and household settings expose humans of all ages to a plethora of …

The impact of air pollution on our epigenome: how far is the evidence?(a systematic review)

R Alfano, Z Herceg, TS Nawrot… - Current environmental …, 2018 - Springer
Abstract Purpose of Review This systematic review evaluated existing evidence linking air
pollution exposure in humans to major epigenetic mechanisms: DNA methylation …