scID: identification of transcriptionally equivalent cell populations across single cell RNA-seq data using discriminant analysis

K Boufea, S Seth, NN Batada - BioRxiv, 2018 - biorxiv.org
The power of single cell RNA sequencing (scRNA-seq) stems from its ability to uncover cell
type-dependent phenotypes, which rests on the accuracy of cell type identification. However …

scID uses discriminant analysis to identify transcriptionally equivalent cell types across single-cell RNA-seq data with batch effect

K Boufea, S Seth, NN Batada - IScience, 2020 - cell.com
The power of single-cell RNA sequencing (scRNA-seq) stems from its ability to uncover cell
type-dependent phenotypes, which rests on the accuracy of cell type identification. However …

Identifying cell types to interpret scRNA-seq data: how, why and more possibilities

Z Wang, H Ding, Q Zou - Briefings in functional genomics, 2020 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has generated numerous data and renewed our
understanding of biological phenomena at the cellular scale. Identification of cell types has …

BCseq: accurate single cell RNA-seq quantification with bias correction

L Chen, S Zheng - Nucleic acids research, 2018 - academic.oup.com
With rapid technical advances, single cell RNA-seq (scRNA-seq) has been used to detect
cell subtypes exhibiting distinct gene expression profiles and to trace cell transitions in …

COMSE: analysis of single-cell RNA-seq data using community detection-based feature selection

Q Luo, Y Chen, X Lan - BMC biology, 2024 - Springer
Background Single-cell RNA sequencing enables studying cells individually, yet high gene
dimensions and low cell numbers challenge analysis. And only a subset of the genes …

One Cell At a Time (OCAT): a unified framework to integrate and analyze single-cell RNA-seq data

CX Wang, L Zhang, B Wang - Genome biology, 2022 - Springer
Integrative analysis of large-scale single-cell RNA sequencing (scRNA-seq) datasets can
aggregate complementary biological information from different datasets. However, most …

Information-theory-based benchmarking and feature selection algorithm improve cell type annotation and reproducibility of single cell RNA-seq data analysis …

Z Ren, M Gerlach, H Shi, AV Misharin, GRS Budinger… - bioRxiv, 2020 - biorxiv.org
Single cell RNA sequencing (scRNA-seq), which promises to enable the quantitative study
of biological processes at the single cell level, are now a routine part of experimental …

ClusterMap: compare multiple single cell RNA-Seq datasets across different experimental conditions

X Gao, D Hu, M Gogol, H Li - Bioinformatics, 2019 - academic.oup.com
Abstract Motivation Single cell RNA-Seq (scRNA-Seq) facilitates the characterization of cell
type heterogeneity and developmental processes. Further study of single cell profiles across …

Classification of low quality cells from single-cell RNA-seq data

T Ilicic, JK Kim, AA Kolodziejczyk, FO Bagger… - Genome biology, 2016 - Springer
Single-cell RNA sequencing (scRNA-seq) has broad applications across biomedical
research. One of the key challenges is to ensure that only single, live cells are included in …

scCATCH: automatic annotation on cell types of clusters from single-cell RNA sequencing data

X Shao, J Liao, X Lu, R Xue, N Ai, X Fan - Iscience, 2020 - cell.com
Recent advancements in single-cell RNA sequencing (scRNA-seq) have facilitated the
classification of thousands of cells through transcriptome profiling, wherein accurate cell …