The power of single-cell RNA sequencing (scRNA-seq) stems from its ability to uncover cell type-dependent phenotypes, which rests on the accuracy of cell type identification. However …
Z Wang, H Ding, Q Zou - Briefings in functional genomics, 2020 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has generated numerous data and renewed our understanding of biological phenomena at the cellular scale. Identification of cell types has …
L Chen, S Zheng - Nucleic acids research, 2018 - academic.oup.com
With rapid technical advances, single cell RNA-seq (scRNA-seq) has been used to detect cell subtypes exhibiting distinct gene expression profiles and to trace cell transitions in …
Q Luo, Y Chen, X Lan - BMC biology, 2024 - Springer
Background Single-cell RNA sequencing enables studying cells individually, yet high gene dimensions and low cell numbers challenge analysis. And only a subset of the genes …
Integrative analysis of large-scale single-cell RNA sequencing (scRNA-seq) datasets can aggregate complementary biological information from different datasets. However, most …
Single cell RNA sequencing (scRNA-seq), which promises to enable the quantitative study of biological processes at the single cell level, are now a routine part of experimental …
X Gao, D Hu, M Gogol, H Li - Bioinformatics, 2019 - academic.oup.com
Abstract Motivation Single cell RNA-Seq (scRNA-Seq) facilitates the characterization of cell type heterogeneity and developmental processes. Further study of single cell profiles across …
Single-cell RNA sequencing (scRNA-seq) has broad applications across biomedical research. One of the key challenges is to ensure that only single, live cells are included in …
X Shao, J Liao, X Lu, R Xue, N Ai, X Fan - Iscience, 2020 - cell.com
Recent advancements in single-cell RNA sequencing (scRNA-seq) have facilitated the classification of thousands of cells through transcriptome profiling, wherein accurate cell …