Different aspects of frailty and COVID-19: points to consider in the current pandemic and future ones

H Hussien, A Nastasa, M Apetrii, I Nistor, M Petrovic… - BMC geriatrics, 2021 - Springer
Background Older adults at a higher risk of adverse outcomes and mortality if they get
infected with Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). These …

Frailty and COVID-19: a systematic scoping review

G Maltese, A Corsonello, M Di Rosa, L Soraci… - Journal of clinical …, 2020 - mdpi.com
Older people have paid a huge toll in terms of mortality during the coronavirus disease-19
(COVID-19) pandemic. Frailty may have contributed to the vulnerability of older people to …

Direct and indirect effects of COVID-19 in frail elderly: interventions and recommendations

MG Pizano-Escalante, LM Anaya-Esparza… - Journal of Personalized …, 2021 - mdpi.com
Frailty is a state of vulnerability to stressors because of a decreased physiological reserve,
resulting in poor health outcomes. This state is related to chronic conditions, many of which …

Approach to COVID-19 in older adults and indications for improving the outcomes

C Tana, L Moffa, K Falasca, J Vecchiet, M Tana… - Annals of …, 2023 - Taylor & Francis
Background: COVID-19 continues to present challenges in the care of older adults with
frailty and/or comorbidities and very old patients, who can be hospitalized with severe …

Presenting features of COVID-19 in older people: relationships with frailty, inflammation and mortality

P Knopp, A Miles, TE Webb, BC Mcloughlin… - European geriatric …, 2020 - Springer
Purpose To describe the clinical features of COVID-19 in older adults, and relate these to
outcomes. Methods A cohort study of 217 individuals (median age 80, IQR 74–85 years; …

Beyond chronological age: frailty and multimorbidity predict in-hospital mortality in patients with coronavirus disease 2019

A Marengoni, A Zucchelli, DL Vetrano… - The Journals of …, 2021 - academic.oup.com
Background We evaluated whether frailty and multimorbidity predict in-hospital mortality in
patients with COVID-19 beyond chronological age. Method A total of 165 patients admitted …

Comparing associations between frailty and mortality in hospitalised older adults with or without COVID-19 infection: a retrospective observational study using …

RK Owen, SP Conroy, N Taub, W Jones… - Age and …, 2021 - academic.oup.com
Background The aim of this study was to describe outcomes in hospitalised older people
with different levels of frailty and COVID-19 infection. Methods We undertook a single-centre …

Frailty as a predictor of mortality among patients with COVID-19: a systematic review and meta-analysis

XM Zhang, J Jiao, J Cao, XP Huo, C Zhu, XJ Wu… - BMC geriatrics, 2021 - Springer
Background A large number of studies have explored the association between frailty and
mortality among COVID-19 patients, with inconsistent results. The aim of this meta-analysis …

Divergent: age, frailty, and atypical presentations of COVID-19 in hospitalized patients

PCE Poco, MJR Aliberti, MB Dias… - The Journals of …, 2021 - academic.oup.com
Background Although frailty has been associated with atypical manifestations of infections,
little is known about COVID-19 presentations in hospitalized frail patients. We aimed to …

Frailty and mortality in hospitalized older adults with COVID-19: retrospective observational study

R De Smet, B Mellaerts, H Vandewinckele… - Journal of the American …, 2020 - Elsevier
Objectives To determine the association between frailty and short-term mortality in older
adults hospitalized for coronavirus disease 2019 (COVID-19). Design Retrospective single …