Circulating tumor DNA detection: A potential tool for colorectal cancer management

H Li, C Jing, J Wu, J Ni, H Sha, X Xu… - Oncology …, 2019 - spandidos-publications.com
Colorectal cancer (CRC) is frequently diagnosed at an advanced stage of the disease, the
pathogenesis of which is influenced by genetic and epigenetic events. Circulating tumor …

[HTML][HTML] Circulating tumor DNA in colorectal cancer: opportunities and challenges

F Bi, Q Wang, Q Dong, Y Wang, L Zhang… - American journal of …, 2020 - ncbi.nlm.nih.gov
Tumor biopsy is the standard method for cancer diagnosis and provides an important
sample for pathological assessment. With the development of precision medicine, liquid …

Circulating tumour DNA, a promising biomarker for the management of colorectal cancer

S Khakoo, A Georgiou, M Gerlinger… - Critical reviews in …, 2018 - Elsevier
Circulating cell free tumour DNA (ctDNA) maintains the same genomic alterations that are
present in the corresponding tumour, thereby allowing for quantitative and qualitative real …

Circulating tumor DNA in precision oncology and its applications in colorectal cancer

MF Arisi, E Dotan, SV Fernandez - International Journal of Molecular …, 2022 - mdpi.com
Circulating tumor DNA (ctDNA) is a component of cell-free DNA (cfDNA) that is shed by
malignant tumors into the bloodstream and other bodily fluids. ctDNA can comprise up to …

Circulating tumor DNA: an emerging tool in gastrointestinal cancers

OB Alese, N Cook, A Ortega-Franco, MB Ulanja, L Tan… - 2022 - christie.openrepository.com
Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA in the bloodstream that
has come from primary or metastatic cancer sites. Neoplasm-specific genetic and epigenetic …

Clinical application of circulating tumour DNA in colorectal cancer

M Loft, YH To, P Gibbs, J Tie - The Lancet Gastroenterology & …, 2023 - thelancet.com
Liquid biopsies that detect circulating tumour DNA (ctDNA) have the potential to
revolutionise the personalised management of colorectal cancer. For patients with early …

[PDF][PDF] Circulating tumor DNA analysis in colorectal cancer: from dream to reality

C Antoniotti, F Pietrantonio, S Corallo… - JCO Precision …, 2019 - air.unimi.it
Liquid biopsy is a minimally invasive approach to obtain circulating materials that originate
from tumor cells through the sampling of body fluids, mainly peripheral blood. Because of its …

Using circulating tumor DNA in colorectal cancer: current and evolving practices

M Malla, JM Loree, PM Kasi, AR Parikh - Journal of Clinical Oncology, 2022 - ascopubs.org
There exists a tremendous opportunity in identifying and determining the appropriate
predictive and prognostic biomarker (s) for risk stratification of patients with colorectal …

Clinical utility of circulating tumor DNA for colorectal cancer

H Osumi, E Shinozaki, K Yamaguchi… - Cancer …, 2019 - Wiley Online Library
Colorectal cancer (CRC) is currently the most common type of cancer in Japan, and its
prognosis has improved because of development of diagnosis and advancement in …

Circulating tumor DNA for early cancer detection

C Fiala, V Kulasingam… - The Journal of Applied …, 2018 - academic.oup.com
Background Cancer cells release circulating tumor DNA (ctDNA) into the bloodstream,
which can now be quantified and examined using novel high-throughput sequencing …