Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers

C Reitz, R Mayeux - Biochemical pharmacology, 2014 - Elsevier
The global prevalence of dementia is as high as 24 million, and has been predicted to
quadruple by the year 2050. In the US alone, Alzheimer disease (AD)–the most frequent …

Epidemiology of Alzheimer disease

C Reitz, C Brayne, R Mayeux - Nature Reviews Neurology, 2011 - nature.com
The global prevalence of dementia is estimated to be as high as 24 million, and is predicted
to double every 20 years through to 2040, leading to a costly burden of disease. Alzheimer …

Alzheimer disease and its growing epidemic: risk factors, biomarkers, and the urgent need for therapeutics

RA Hickman, A Faustin, T Wisniewski - Neurologic clinics, 2016 - neurologic.theclinics.com
Alzheimer disease (AD) represents one of the greatest medical challenges of this century;
the condition is becoming increasingly prevalent worldwide and as yet, no effective …

Epidemiology of Alzheimer disease

R Mayeux, Y Stern - Cold Spring Harbor …, 2012 - perspectivesinmedicine.cshlp.org
The global prevalence of dementia has been estimated to be as high as 24 million, and is
predicted to double every 20 years until at least 2040. As the population worldwide …

Epidemiology of dementia: the burden on society, the challenges for research

FJ Wolters, MA Ikram - Biomarkers for Alzheimer's disease drug …, 2018 - Springer
Dementia is among the leading causes of death and disability. Due to the ageing
population, its prevalence is expected to nearly triple worldwide by 2050, urging the …

[HTML][HTML] Modifiable risk factors for Alzheimer's disease

GA Edwards III, N Gamez, G Escobedo Jr… - Frontiers in aging …, 2019 - frontiersin.org
Since first described in the early 1900s, Alzheimer's disease (AD) has risen exponentially in
prevalence and concern. Research still drives to understand the etiology and pathogenesis …

Is Alzheimer disease a disease?

AD Korczyn, LT Grinberg - Nature Reviews Neurology, 2024 - nature.com
Dementia, a prevalent condition among older individuals, has profound societal
implications. Extensive research has resulted in no cure for what is perceived as the most …

Causes and patterns of dementia: an update in the era of redefining Alzheimer's disease

BD James, DA Bennett - Annual review of public health, 2019 - annualreviews.org
The burden of dementia continues to increase as the population ages, with no disease-
modifying treatments available. However, dementia risk appears to be decreasing, and …

[HTML][HTML] Is Alzheimer's disease a systemic disease?

JK Morris, RA Honea, ED Vidoni, RH Swerdlow… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Although Alzheimer's disease (AD) is the most common neurodegenerative disease, the
etiology of AD is not well understood. In some cases, genetic factors explain AD risk, but a …

[HTML][HTML] When does Alzheimer′ s disease really start? The role of biomarkers

A Lloret, D Esteve, MA Lloret, A Cervera-Ferri… - International journal of …, 2019 - mdpi.com
While Alzheimer's disease (AD) classical diagnostic criteria rely on clinical data from a
stablished symptomatic disease, newer criteria aim to identify the disease in its earlier …