In this chapter we describe a computer simulation system focused on the immune response.
The objective of this study is to show to what extent a computational model can be used as …

High-throughput technologies allow the investigation of vaccine-induced immune responses
at system and molecular levels. These are currently being used to unravel new molecular …

This supplement, Nature Medicine's first, is dedicated entirely to the subject of vaccines. Of
course it has been known for decades that a single vaccine can save more lives and more …

As we enter the 21st century, we can prepare nearly any antigen for use as a vaccine. The
difficulties we face are in identifying protective antigens and inducing the immune system to …

Ten years of the Global Alliance for Vaccines and Immunization: challenges and progress |
Nature Immunology Skip to main content Thank you for visiting nature.com. You are using a …

Vaccines are the most cost effective public health measure for preventing viral infection and
limiting epidemic spread within susceptible populations. However, the efficacy of current …

The impact of vaccines on public health and wellbeing has been profound. Smallpox has
been eradicated, polio is nearing eradication, and multiple diseases have been eliminated …

Introduction Conventionally, vaccines are thought to induce a specific immune response
directed against a target pathogen. Long recognized but poorly understood nonspecific …

The spectacular increase of life expectancy in many countries of the world is mainly due to
the conquest of infectious diseases by vaccines, hygiene, and antibiotics. Vaccines have …

Vaccines are the most effective medical intervention due to their continual success in
preventing infections and improving mortality worldwide. Early vaccines were developed …