Metabolomics comprises the methods and techniques that are used to measure the small
molecule composition of biofluids and tissues, and is actually one of the most rapidly …

The thousands of features commonly observed when performing untargeted metabolomics
with quadrupole time-of-flight (QTOF) and Orbitrap mass spectrometers often correspond to …

Highlights•Metabolomics provides a functional read-out of the physiological status of an
organism.•A precise (dynamic) description of the clinical phenotype is missing for complex …

Highlights•Deeper understanding of metabolisms is accelerated by computational
metabolomics.•Advances for metabolite identification, classification, and prediction are …

MS has evolved as a critical component in metabolomics, which seeks to answer biological
questions through large-scale qualitative and quantitative analyses of the metabolome. MS …

Metabolomics refers to the large-scale detection, quantification, and analysis of small
molecules (metabolites) in biological media. Although metabolomics, alone or combined …

Metabolomics aims to measure and characterise the complex composition of metabolites in
a biological system. Metabolomics studies involve sophisticated analytical techniques such …

Modern analytical technologies afford comprehensive and quantitative investigation of a
multitude of different metabolites. Typical metabolomic experiments can therefore produce …

Recent technological advances in accurate mass spectrometry and data analysis have
revolutionized metabolomics experimentation. Activity‐based and global metabolomic …

Metabolomics deals with multiple and complex chemical reactions within living organisms
and how these are influenced by external or internal perturbations. It lies at the heart of …