Reappearance of effector T cells is associated with recovery from COVID-19

I Odak, J Barros-Martins, B Bošnjak, K Stahl, S David… - …, 2020 - thelancet.com
Background Elucidating the role of T cell responses in COVID-19 is of utmost importance to
understand the clearance of SARS-CoV-2 infection. Methods 30 hospitalized COVID-19 …

Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19)

B Diao, C Wang, Y Tan, X Chen, Y Liu, L Ning… - Frontiers in …, 2020 - frontiersin.org
Background: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed great threat to human health …

T‐cell recovery and evidence of persistent immune activation 12 months after severe COVID‐19

P Taeschler, S Adamo, Y Deng, C Cervia… - Allergy, 2022 - Wiley Online Library
Background T‐cell lymphopenia and functional impairment is a hallmark of severe acute
coronavirus disease 2019 (COVID‐19). How T‐cell numbers and function evolve at later …

Reduced numbers of T cells and B cells correlates with persistent SARS-CoV-2 presence in non-severe COVID-19 patients

B Liu, J Han, X Cheng, L Yu, L Zhang, W Wang, L Ni… - Scientific reports, 2020 - nature.com
COVID-19 has been widely spreading. We aimed to examine adaptive immune cells in non-
severe patients with persistent SARS-CoV-2 shedding. 37 non-severe patients with …

T cell perturbations persist for at least 6 months following hospitalization for COVID-19

M Govender, FR Hopkins, R Göransson… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is being extensively studied, and much remains unknown regarding the long-term
consequences of the disease on immune cells. The different arms of the immune system are …

Remodeling of T cell dynamics during long COVID is dependent on severity of SARS-CoV-2 infection

M Wiech, P Chroscicki, J Swatler, D Stepnik… - Frontiers in …, 2022 - frontiersin.org
Several COVID-19 convalescents suffer from the post-acute COVID-syndrome (PACS)/long
COVID, with symptoms that include fatigue, dyspnea, pulmonary fibrosis, cognitive …

Regulatory T cells as predictors of clinical course in hospitalised COVID-19 patients

S Caldrer, C Mazzi, M Bernardi, M Prato… - Frontiers in …, 2021 - frontiersin.org
Background The host immune response has a prominent role in the progression and
outcome of SARS-CoV-2 infection. Lymphopenia has been described as an important …

Peripheral CD4+ T cell subsets and antibody response in COVID-19 convalescent individuals

F Gong, Y Dai, T Zheng, L Cheng… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Marked progress is achieved in understanding the physiopathology of
coronavirus disease 2019 (COVID-19), which caused a global pandemic. However, the …

Decreased T cell populations contribute to the increased severity of COVID-19

R Liu, Y Wang, J Li, H Han, Z Xia, F Liu, K Wu… - Clinica Chimica …, 2020 - Elsevier
Background We observe changes of the main lymphocyte subsets (CD16+ CD56, CD19,
CD3, CD4, and CD8) in COVID-19-infected patients and explore whether the changes are …

Alterations in T and B cell function persist in convalescent COVID-19 patients

HA Shuwa, TN Shaw, SB Knight, K Wemyss… - Med, 2021 - cell.com
Background Emerging studies indicate that some coronavirus disease 2019 (COVID-19)
patients suffer from persistent symptoms, including breathlessness and chronic fatigue; …