Life expectancy has been on the rise for the past few decades, but healthy life expectancy
has not kept pace, leading to a global burden of age-associated disorders. Advancing age is …

Ageing and age-related diseases share some basic mechanistic pillars that largely
converge on inflammation. During ageing, chronic, sterile, low-grade inflammation—called …

'Inflammaging'refers to the chronic, low-grade inflammation that characterizes aging.
Inflammaging is macrophage centered, involves several tissues and organs, including the …

Background Old age is characterized by a peculiar low-grade, chronic, and “sterile”
inflammatory state, which has been termed “inflammaging.” This is believed to substantially …

Inflammaging is characterized by the upregulation of the inflammatory response that occurs
with advancing age; its roots are strongly embedded in evolutionary theory. Inflammaging is …

Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

Human aging is characterized by a chronic, low-grade inflammation, and this phenomenon
has been termed as “inflammaging.” Inflammaging is a highly significant risk factor for both …

Ageing of the global population has become a public health concern with an important socio-
economic dimension. Ageing is characterized by an increase in the concentration of …

The possibility to control inflamm-ageing represents a powerful tool to modulate and
counteract the major age-related pathologies and it is urgent to clarify the shady areas of the …

A chronic disease in older adults usually runs a course that is less predictable than in
younger individuals. Unexplained variations in disease incidence, prognosis, therapeutic …