Cervical cancer is the leading cause of death among women with cancer worldwide. Here,
we performed an integrative analysis of Illumina HumanMethylation450K and RNA-seq data …

Purpose: Epigenetic host cell changes involved in cervical cancer development following a
persistent high-risk human papillomavirus (hrHPV) infection, provide promising markers for …

The oncogenic human papilloma viruses (HPVs) are associated with precancerous cervical
lesions and development of cervical cancer. The DNA methylation signatures of the host …

Using DNA methylation biomarkers in cancer detection is a potential direction in clinical
testing. Some methylated genes have been proposed for cervical cancer detection; …

ABSTRACT DNA methylation status is closely associated with diverse diseases, and is
generally more stable than gene expression, thus abnormal DNA methylation could be …

OBJECTIVE: We wanted to identify the most promising methylation marker candidates for
cervical cancer early detection. METHODS: A systematic literature review was performed in …

Background Despite of the trend that the application of DNA methylation as a biomarker for
cancer detection is promising, clinically applicable genes are few. Therefore, we looked for …

Background Cancer cells undergo massive alterations to their DNA methylation patterns that
result in aberrant gene expression and malignant phenotypes. However, the mechanisms …

Abstract Background Data mining of The Cancer Genome Atlas (TCGA) data has
significantly facilitated cancer genome research and provided unprecedented opportunities …

BACKGROUND: DNA methylation may be used a potential biomarker for detecting cervical
cancer. The authors of this report used quantitative methylation analysis of 4 genes in a full …