[HTML][HTML] The business of anti-aging science

JP De Magalhães, M Stevens, D Thornton - Trends in biotechnology, 2017 - cell.com
Age-related conditions are the leading causes of death and health-care costs. Reducing the
rate of aging would have enormous medical and financial benefits. Myriad genes and …

Drugs that modulate aging: the promising yet difficult path ahead

BK Kennedy, JK Pennypacker - Translational research, 2014 - Elsevier
Once a backwater in medical sciences, aging research has emerged and now threatens to
take the forefront. This dramatic change of stature is driven from 3 major events. First and …

[HTML][HTML] The future of aging therapies

EC Hadley, EG Lakatta, M Morrison-Bogorad… - Cell, 2005 - cell.com
Advances in understanding aging processes and their consequences are leading to the
development of therapies to slow or reverse adverse changes formerly considered to be" …

[HTML][HTML] ARDD 2020: from aging mechanisms to interventions

GV Mkrtchyan, K Abdelmohsen, P Andreux… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Aging is emerging as a druggable target with growing interest from academia, industry and
investors. New technologies such as artificial intelligence and advanced screening …

From discoveries in ageing research to therapeutics for healthy ageing

J Campisi, P Kapahi, GJ Lithgow, S Melov, JC Newman… - Nature, 2019 - nature.com
For several decades, understanding ageing and the processes that limit lifespan have
challenged biologists. Thirty years ago, the biology of ageing gained unprecedented …

[HTML][HTML] Why is aging conserved and what can we do about it?

JN Pitt, M Kaeberlein - PLoS biology, 2015 - journals.plos.org
The field of aging research has progressed rapidly over the past few decades. Genetic
modulators of aging rate that are conserved over a broad evolutionary distance have now …

Can aging be'drugged'?

CE Riera, A Dillin - Nature medicine, 2015 - nature.com
The engines that drive the complex process of aging are being identified by model-organism
research, thereby providing potential targets and rationale for drug studies. Several studies …

[HTML][HTML] Aging: a common driver of chronic diseases and a target for novel interventions

BK Kennedy, SL Berger, A Brunet, J Campisi… - Cell, 2014 - ncbi.nlm.nih.gov
Mammalian aging can be delayed with genetic, dietary and pharmacologic approaches.
Given that the elderly population is dramatically increasing and that aging is the greatest risk …

[HTML][HTML] Longevity and aging

M Kaeberlein - F1000prime reports, 2013 - ncbi.nlm.nih.gov
Research into the biology of aging seeks to understand the basic mechanisms of aging, with
the goal of extending the period of life spent free from chronic disease and disability. Aging …

[图书][B] The Evolution of Aging: How new theories will change the future of medicine

TC Goldsmith - 2006 - books.google.com
Why do we age? Scientists have been baffled by this question for centuries and disagree
regarding even the general nature of aging. Is aging the result of fundamental limitations that …