BK Kennedy, JK Pennypacker - Translational research, 2014 - Elsevier
Once a backwater in medical sciences, aging research has emerged and now threatens to take the forefront. This dramatic change of stature is driven from 3 major events. First and …
Advances in understanding aging processes and their consequences are leading to the development of therapies to slow or reverse adverse changes formerly considered to be" …
Aging is emerging as a druggable target with growing interest from academia, industry and investors. New technologies such as artificial intelligence and advanced screening …
For several decades, understanding ageing and the processes that limit lifespan have challenged biologists. Thirty years ago, the biology of ageing gained unprecedented …
JN Pitt, M Kaeberlein - PLoS biology, 2015 - journals.plos.org
The field of aging research has progressed rapidly over the past few decades. Genetic modulators of aging rate that are conserved over a broad evolutionary distance have now …
The engines that drive the complex process of aging are being identified by model-organism research, thereby providing potential targets and rationale for drug studies. Several studies …
Mammalian aging can be delayed with genetic, dietary and pharmacologic approaches. Given that the elderly population is dramatically increasing and that aging is the greatest risk …
M Kaeberlein - F1000prime reports, 2013 - ncbi.nlm.nih.gov
Research into the biology of aging seeks to understand the basic mechanisms of aging, with the goal of extending the period of life spent free from chronic disease and disability. Aging …
Why do we age? Scientists have been baffled by this question for centuries and disagree regarding even the general nature of aging. Is aging the result of fundamental limitations that …