Much research indicates that exposure to early life adversity (ELA) predicts chronic
inflammatory activity, increasing one's risk of developing diseases of aging later in life …

It is proposed that environmental exposures in early life influence immune programming.
Specifically, socioeconomic disadvantage is thought to program an immune phenotype that …

Accumulating evidence suggests that the experience of early life adversity is a risk factor for
a range of poor outcomes across development, including poor physical health in adulthood …

There is considerable evidence that stressful early life events influence a variety of physical
health problems later in life. Childhood adversity has been linked to elevated rates of …

There is strong evidence that chronic, systemic inflammation hastens onset of the diseases
of old age that ultimately lead to death. Importantly, several studies suggest that childhood …

It has been suggested that childhood adversity programs an inflammatory phenotype
characterized by higher levels of systemic inflammation and increased health risk in later …

Early life adversity (ELA) is associated with a higher risk for diseases in adulthood. Although
the pathophysiological effects of ELA are varied, there may be a unifying role for the immune …

Childhood adversity is associated with a host of mental and physical health problems across
the lifespan. Individuals who have experienced childhood adversity (eg, child abuse and …

Early life adversity (ELA) is a risk factor for early onset morbidities and mortality, a
relationship that may be driven in part by immune system dysregulation. One mechanism of …

Early life stressors are associated with elevated inflammation, a key physiological risk factor
for disease. However, the mechanisms by which early stress leads to inflammation remain …