Longevity and aging are two sides of the same coin, as they both derive from the interaction
between genetic and environmental factors. Aging is a complex, dynamic biological process …

The interrelation of the processes of immunity and senescence now receives an
unprecedented emphasis during the COVID-19 pandemic, which brings to the fore the …

Chronic consumption of a Western diet along with sedentary behaviour causes chronic
metabolic inflammation (termed metaflammation) and is 'memorized'by innate immune cells …

Simple Summary Aging affects all cells of the body, leading to impaired system function.
Although scientists are beginning to identify some mechanisms underlying the aging …

Abstract The National Institutes of Health (NIH) Geroscience Interest Group (GSIG)
sponsored workshop, The Role of Inflammation in Age-Related Disease, was held …

Aging is characterized by the functional decline of tissues and organs and increased risk of
aging-associated disorders, which pose major societal challenges and are a public health …

The gut microbiota shows a wide inter-individual variation, but its within-individual variation
is relatively stable over time. A functional core microbiome, provided by abundant bacterial …

Introduction. Age is the primary risk factor for major human chronic diseases, including
cardiovascular disorders, cancer, type 2 diabetes, and neurodegenerative diseases …

Obesity and aging represent major health burdens to the global adult population. Both
conditions promote the development of associated metabolic diseases such as insulin …

Gut microbiota is established during birth and evolves with age, mostly maintaining the
commensal relationship with the host. A growing body of clinical evidence suggests an …