Mass spectrometry measures of plasma Aβ, tau and P‐tau isoforms' relationship to amyloid PET, tau PET, and clinical stage of Alzheimer's disease: Clinical study …

RJ Bateman, NR Barthelemy… - Alzheimer's & …, 2020 - Wiley Online Library
Background Recent advances in understanding the links between amyloid‐beta (Aβ) and
specific tau isoforms in brain, cerebrospinal fluid (CSF), and blood indicate that a cascade of …

CSF and blood plasma mass spectrometry measures of Aβ, tau, and NfL species and longitudinal relationship to preclinical and clinical staging of amyloid and tau …

RJ Bateman, NR Barthelemy… - Alzheimer's & …, 2021 - Wiley Online Library
Background Recent advances in the development of novel Alzheimer's disease (AD)
measures of amyloid, tau, and neurodegeneration in cerebrospinal fluid (CSF) and blood …

Blood‐based biomarkers of Alzheimer disease as measured by a mass spectrometry assay are as accurate as CSF tests

SE Schindler, NR Barthélemy, BA Saef… - Alzheimer's & …, 2023 - Wiley Online Library
Background Especially because disease‐modifying treatments (DMTs) for Alzheimer
disease (AD) are likely to become more available soon, highly accurate AD blood tests for …

Characterization of Alzheimer's tau biomarker discordance using plasma, CSF, and PET

Y Guo, YY Huang, XN Shen, SD Chen, H Hu… - Alzheimer's research & …, 2021 - Springer
Background We aimed to investigate the tau biomarker discrepancies of Alzheimer's
disease (AD) using plasma tau phosphorylated at threonine 181 (p-tau181), cerebrospinal …

Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease

S Janelidze, D Bali, NJ Ashton, NR Barthélemy… - Brain, 2023 - academic.oup.com
Plasma phospho-tau (p-tau) species have emerged as the most promising blood-based
biomarkers of Alzheimer's disease. Here, we performed a head-to-head comparison of p …

Amyloid, pTau, NfL, and GFAP as biomarkers for Alzheimer's disease: Clinical study results of AD blood biomarkers

EH Thijssen, IMW Verberk, E Stoops… - Alzheimer's & …, 2020 - Wiley Online Library
Background Alzheimer's disease (AD) is a multifactorial disease, with ongoing amyloid and
tau accumulation, axonal damage and astrocytosis. Blood‐based biomarkers reflecting …

Associations of the A/T/N profiles in PET, CSF, and plasma biomarkers with Alzheimer's disease neuropathology at autopsy

ZB Wang, L Tan, PY Gao, YH Ma, Y Fu… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION To examine the extent to which positron emission tomography (PET)‐,
cerebrospinal fluid (CSF)‐, and plasma‐related amyloid‐β/tau/neurodegeneration (A/T/N) …

Plasma p‐tau181, p‐tau217, and other blood‐based Alzheimer's disease biomarkers in a multi‐ethnic, community study

AM Brickman, JJ Manly, LS Honig… - Alzheimer's & …, 2021 - Wiley Online Library
Abstract Introduction Blood‐based Alzheimer's disease (AD) biomarkers provide
opportunities for community studies and across ethnic groups. We investigated blood …

Cerebrospinal fluid and plasma tau as a biomarker for brain tauopathy

M Shoji - Tau Biology, 2019 - Springer
Cerebrospinal fluid (CSF) tau and phosphorylated tau (ptau) are definite biomarkers of
Alzheimer's disease (AD). After discovery of presence and increased levels tau in CSF from …

Equivalence of plasma p‐tau217 with cerebrospinal fluid in the diagnosis of Alzheimer's disease

J Therriault, S Servaes, C Tissot… - Alzheimer's & …, 2023 - Wiley Online Library
INTRODUCTION Plasma biomarkers are promising tools for Alzheimer's disease (AD)
diagnosis, but comparisons with more established biomarkers are needed. METHODS We …