Reporting dinaciclib and theodrenaline as a multitargeted inhibitor against SARS-CoV-2: an in-silico study

S Ahmad, M Pasha KM, K Raza… - Journal of …, 2023 - Taylor & Francis
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is one of the rapid
spreading coronaviruses that belongs to the Coronaviridae family. The rapidly evolving …

Potential inhibitors for the novel coronavirus (SARS-CoV-2)

Y Han, Z Wang, J Ren, Z Wei, J Li - Briefings in Bioinformatics, 2021 - academic.oup.com
The lack of a vaccine or any effective treatment for the aggressive novel coronavirus disease
(COVID-19) has created a sense of urgency for the discovery of effective drugs. Several …

Discovery of potent SARS-CoV-2 inhibitors from approved antiviral drugs via docking and virtual screening

S Chtita, A Belhassan, A Aouidate… - … chemistry & high …, 2021 - ingentaconnect.com
Background: Coronavirus Disease 2019 (COVID-19) pandemic continues to threaten
patients, societies and healthcare systems around the world. There is an urgent need to …

[HTML][HTML] A contemporary review on the important role of in silico approaches for managing different aspects of COVID-19 crisis

M Moradi, R Golmohammadi, A Najafi… - Informatics in Medicine …, 2022 - Elsevier
In the last century, the emergence of in silico tools has improved the quality of healthcare
studies by providing high quality predictions. In the case of COVID-19, these tools have …

Potential anti-viral activity of approved repurposed drug against main protease of SARS-CoV-2: an in silico based approach

S Mahanta, P Chowdhury, N Gogoi… - Journal of …, 2021 - Taylor & Francis
Abstract The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which was
first reported in Wuhan province of China, has become a deadly pandemic causing …

[HTML][HTML] Phytochemicals against SARS-CoV as potential drug leads

SS Swain, SK Panda, W Luyten - Biomedical Journal, 2021 - Elsevier
The newly emerged SARS-CoV-2 strains from the coronavirus (CoV) family is causing one
of the most disruptive pandemics of the past century. Developing antiviral drugs is a …

Rapid establishment of traditional Chinese medicine prevention and treatment of 2019-nCoV based on clinical experience and molecular docking

M Niu, RL Wang, ZX Wang, P Zhang, ZF Bai… - Zhongguo Zhong yao …, 2020 - europepmc.org
The coronavirus disease 2019 (COVID-19) is raging in China and more than 20 other
countries and regions since the middle of December 2019. Currently, there is no specific …

COVID-19: characteristics and therapeutics

R Chilamakuri, S Agarwal - Cells, 2021 - mdpi.com
Novel coronavirus (COVID-19 or 2019-nCoV or SARS-CoV-2), which suddenly emerged in
December 2019 is still haunting the entire human race and has affected not only the …

Decoding SARS-CoV-2 transmission and evolution and ramifications for COVID-19 diagnosis, vaccine, and medicine

R Wang, Y Hozumi, C Yin, GW Wei - Journal of chemical …, 2020 - ACS Publications
Tremendous effort has been given to the development of diagnostic tests, preventive
vaccines, and therapeutic medicines for coronavirus disease 2019 (COVID-19) caused by …

Methodology-centered review of molecular modeling, simulation, and prediction of SARS-CoV-2

K Gao, R Wang, J Chen, L Cheng, J Frishcosy… - Chemical …, 2022 - ACS Publications
Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …