[图书][B] Drug discovery from nature

S Grabley, R Thiericke - 1998 - books.google.com
Drug discovery strategies for both pharmaceutical and agrochemical applications are at a
stage of rapid development. More than 30% of sales of drugs for human consumption …

Natural products: a continuing source of novel drug leads

GM Cragg, DJ Newman - Biochimica et Biophysica Acta (BBA)-General …, 2013 - Elsevier
BACKGROUND: Nature has been a source of medicinal products for millennia, with many
useful drugs developed from plant sources. Following discovery of the penicillins, drug …

International collaboration in drug discovery and development from natural sources

GM Cragg, DJ Newman - Pure and applied chemistry, 2005 - degruyter.com
Nature has been a source of medicinal agents for thousands of years, and an impressive
number of modern drugs have been isolated from natural sources, particularly plants, with …

Natural products and combinatorial chemistry: back to the future

JY Ortholand, A Ganesan - Current opinion in chemical biology, 2004 - Elsevier
The introduction of high-throughput synthesis and combinatorial chemistry has precipitated
a global decline in the screening of natural products by the pharmaceutical industry. Some …

[图书][B] Natural products chemistry: sources, separations and structures

R Cooper, G Nicola - 2014 - books.google.com
Notoriously cumbersome to isolate and challenging to synthesize, the path of natural
products to viable drugs is an arduous journey. Yet compounds isolated from nature may …

Natural products for drug discovery in the 21st century: innovations for novel drug discovery

NE Thomford, DA Senthebane, A Rowe… - International journal of …, 2018 - mdpi.com
The therapeutic properties of plants have been recognised since time immemorial. Many
pathological conditions have been treated using plant-derived medicines. These medicines …

[PDF][PDF] Role of natural products in drug discovery process

AA Siddiqui, F Iram, S Siddiqui, K Sahu - Int J Drug Dev Res, 2014 - researchgate.net
Natural products and their related moieties have historically been incredible as a source of
therapeutic agents. In last 5-10 years, research into natural products in the pharmaceutical …

Natural products in drug discovery: present status and perspectives

G Molinari - Pharmaceutical Biotechnology, 2009 - Springer
Natural products and their derivatives have been and continue to be rich sources for drug
discovery. However, natural products are not drugs. They are produce in nature and through …

Will natural products remain an important source of drug research for the future?

LJ Nisbet, M Moore - Current opinion in biotechnology, 1997 - Elsevier
In the highly competitive environment of contemporary pharmaceutical research, natural
products provide a unique element of molecular diversity and biological functionality which …

Modern methods to produce natural-product libraries

U Abel, C Koch, M Speitling, FG Hansske - Current Opinion in Chemical …, 2002 - Elsevier
Natural sources offer a wealth of chemically diverse compounds that have been evolutionary
preselected to modulate biochemical pathways. Several industrial and academic groups are …