Plasma glial fibrillary acidic protein in the Alzheimer disease continuum: relationship to other biomarkers, differential diagnosis, and prediction of clinical progression

XN Shen, SY Huang, M Cui, QH Zhao, Y Guo… - Clinical …, 2023 - academic.oup.com
Background Plasma glial fibrillary acidic protein (GFAP) has emerged as a promising
biomarker in neurological disorders, but further evidence is required in relation to its …

Cross‐sectional and longitudinal evaluation of plasma glial fibrillary acidic protein to detect and predict clinical syndromes of Alzheimer's disease

M Ally, MA Sugarman, H Zetterberg… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction This study examined plasma glial fibrillary acidic protein (GFAP) as a biomarker
of cognitive impairment due to Alzheimer's disease (AD) with and against plasma …

Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Aβ‐PET, neurodegeneration, and cognition

P Chatterjee, L Vermunt, BA Gordon… - Alzheimer's & …, 2023 - Wiley Online Library
Background Glial fibrillary acidic protein (GFAP) is a promising candidate blood‐based
biomarker for Alzheimer's disease (AD) diagnosis and prognostication. The timing of its …

Clinical and biological relevance of glial fibrillary acidic protein in Alzheimer's disease

Z Yang, K Sreenivasan, EN Toledano Strom… - Alzheimer's Research & …, 2023 - Springer
Introduction There is a tremendous need for identifying reliable blood-based biomarkers for
Alzheimer's disease (AD) that are tied to the biological ATN (amyloid, tau and …

Glial fibrillary acidic protein in serum is increased in Alzheimer's disease and correlates with cognitive impairment

P Oeckl, S Halbgebauer… - Journal of …, 2019 - content.iospress.com
Reliable blood biomarkers for Alzheimer's disease (AD) are missing. We measured
astroglial GFAP in patients with AD (n= 28), frontotemporal dementia (bvFTD, n= 35) …

Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer's disease

P Chatterjee, S Pedrini, E Stoops, K Goozee… - Translational …, 2021 - nature.com
Glial fibrillary acidic protein (GFAP), an astrocytic cytoskeletal protein, can be measured in
blood samples, and has been associated with Alzheimer's disease (AD). However, plasma …

Plasma glial fibrillary acidic protein detects Alzheimer pathology and predicts future conversion to Alzheimer dementia in patients with mild cognitive impairment

C Cicognola, S Janelidze, J Hertze… - Alzheimer's research & …, 2021 - Springer
Introduction Plasma glial fibrillary acidic protein (GFAP) is a marker of astroglial activation
and astrocytosis. We assessed the ability of plasma GFAP to detect Alzheimer's disease …

Plasma glial fibrillary acidic protein levels differ along the spectra of amyloid burden and clinical disease stage

BM Asken, FM Elahi, R La Joie, A Strom… - Journal of …, 2020 - content.iospress.com
Background: Measuring plasma glial fibrillary acidic protein (GFAP) alongside cortical
amyloid-β (Aβ) may shed light on astrocytic changes in aging and Alzheimer's disease (AD) …

Serum glial fibrillary acidic protein (GFAP) is a marker of disease severity in frontotemporal lobar degeneration

A Benussi, NJ Ashton, TK Karikari… - Journal of …, 2020 - content.iospress.com
Background: It is still unknown if serum glial fibrillary acidic protein (GFAP) is a useful marker
in frontotemporal lobar degeneration (FTLD). Objective: To assess the diagnostic and …

Association of plasma glial fibrillary acidic protein (GFAP) with neuroimaging of Alzheimer's disease and vascular pathology

D Shir, J Graff‐Radford, EI Hofrenning… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction: Plasma glial fibrillary acidic protein (GFAP) may be associated with amyloid
burden, neurodegeneration, and stroke but its specificity for Alzheimer's disease (AD) in the …