Early experiences of threat, but not deprivation, are associated with accelerated biological aging in children and adolescents

JA Sumner, NL Colich, M Uddin, D Armstrong… - Biological …, 2019 - Elsevier
Background Recent conceptual models argue that early life adversity (ELA) accelerates
development, which may contribute to poor mental and physical health outcomes. Evidence …

Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.

NL Colich, ML Rosen, ES Williams… - Psychological …, 2020 - psycnet.apa.org
Life history theory argues that exposure to early life adversity (ELA) accelerates
development, although existing evidence for this varies. We present a meta-analysis and …

Early adversities accelerate epigenetic aging into adulthood: a 10‐year, within‐subject analysis

WE Copeland, L Shanahan… - Journal of Child …, 2022 - Wiley Online Library
Background Longitudinal studies are needed to clarify whether early adversities are
associated with advanced methylation age or if they actually accelerate methylation aging …

Early-life adversity accelerates child and adolescent development

J Belsky - Current Directions in Psychological Science, 2019 - journals.sagepub.com
Most developmental work regards adverse developmental experiences as forces that
undermine well-being. Here, I present an alternative—or complementary—view …

The effects of early life adversity on children's mental health and cognitive functioning

M Wade, L Wright, KE Finegold - Translational Psychiatry, 2022 - nature.com
Emerging evidence suggests that partially distinct mechanisms may underlie the association
between different dimensions of early life adversity (ELA) and psychopathology in children …

Neurostructural traces of early life adversities: A meta-analysis exploring age-and adversity-specific effects

TM Pollok, A Kaiser, EJ Kraaijenvanger… - Neuroscience & …, 2022 - Elsevier
Early life adversities (ELAs) are associated with an increased risk of psychopathology, with
studies suggesting a relation to structural brain alterations. Given the recently growing …

Early life adversity, pubertal timing, and epigenetic age acceleration in adulthood

EJ Hamlat, AA Prather, S Horvath… - Developmental …, 2021 - Wiley Online Library
Background Given associations linking early life adversity, pubertal timing, and biological
aging, we examined the direct and indirect effects of early life trauma on adult biological …

Neurobiological markers of resilience to early-life adversity during adolescence

ASM Leal, JA Silvers - Biological Psychiatry: Cognitive Neuroscience and …, 2021 - Elsevier
Early-life adversity (ELA) exposure (eg, trauma, abuse, neglect, or institutional care) is a
precursor to poor physical and mental health outcomes and is implicated in 30% of adult …

Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children

S Marini, KA Davis, TW Soare, Y Zhu… - …, 2020 - Elsevier
Objectives Exposure to adversity has been linked to accelerated biological aging, which in
turn has been shown to predict numerous physical and mental health problems. In recent …

Earlier age at menarche as a transdiagnostic mechanism linking childhood trauma with multiple forms of psychopathology in adolescent girls

NL Colich, JM Platt, KM Keyes, JA Sumner… - Psychological …, 2020 - cambridge.org
BackgroundAlthough early life adversity (ELA) increases risk for psychopathology,
mechanisms linking ELA with the onset of psychopathology remain poorly understood …