Rapidly increasing numbers of older people present many countries with growing social and
economic challenges. Yet despite the far-reaching implications of ageing, its biological basis …

The rapidly increasing aging prevalence, complexity, and heterogeneity pose the scientific
and medical communities in front of challenges. These are delivered by gaps between basic …

Given the unprecedented phenomenon of population ageing, studies have increasing
captured the heterogeneity within the ageing process. In this context, the concept of …

Diverse individuals age at different rates and display variable susceptibilities to tissue aging,
functional decline and aging-related diseases. Centenarians, exemplifying extreme …

The rising numbers and proportion of aged individuals in the population is a global
demographic trend. The diseases associated with ageing are becoming more prevalent, and …

Despite increasing research efforts, there is a lack of consensus on defining aging or health.
To understand the underlying processes, and to foster the development of targeted …

The field of aging is at a precipice. Attention and funding are increasingly focused on this
area, and exciting, fundamentally important findings are being reported literally every day …

The authors outline the progression of thought on the mechanism of the aging process,
giving emphasis to environmental factors that influence genetic events. Discussion is limited …

A better understanding of the biological and environmental variables that contribute to
exceptional longevity has the potential to inform the treatment of geriatric diseases and help …

Metabolomics is the latest 'omics' technology and systems biology science that allows for
comprehensive profiling of small-molecule metabolites in biological systems at a specific …