Human brain microvascular endothelial cells exposure to SARS-CoV-2 leads to inflammatory activation through NF-κB non-canonical pathway and mitochondrial …

CS Motta, S Torices, BG da Rosa, AC Marcos… - Viruses, 2023 - mdpi.com
Neurological effects of COVID-19 and long-COVID-19, as well as neuroinvasion by SARS-
CoV-2, still pose several questions and are of both clinical and scientific relevance. We …

[HTML][HTML] SARS-CoV-2 infection of human brain microvascular endothelial cells leads to inflammatory activation through NF-κB non-canonical pathway and …

S Torices, C Motta, B da Rosa, A Marcos… - Research …, 2022 - ncbi.nlm.nih.gov
Neurological effects of COVID-19 and long-COVID-19 as well as neuroinvasion by SARS-
CoV-2 still pose several questions and are of both clinical and scientific relevance. We …

The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2

S Krasemann, U Haferkamp, S Pfefferle, MS Woo… - Stem cell reports, 2022 - cell.com
Neurological complications are common in COVID-19. Although SARS-CoV-2 has been
detected in patients' brain tissues, its entry routes and resulting consequences are not well …

SARS-CoV-2 productively infects human brain microvascular endothelial cells

RC Yang, K Huang, HP Zhang, L Li, YF Zhang… - Journal of …, 2022 - Springer
Background The emergence of the novel, pathogenic severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has caused a global health emergency. SARS-CoV-2 is highly …

Role of endothelial cells and angiotensin converting enzyme-II in COVID-19 and brain damages post-infection

R Mehboob, JP von Kries, K Ehsan… - Frontiers in …, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) causes coronavirus
disease 2019 (COVID-19), which became a pandemic in late 2019 and early 2020. Apart …

Role of aging in blood–brain barrier dysfunction and susceptibility to SARS-CoV-2 infection: impacts on neurological symptoms of COVID-19

D Adesse, L Gladulich, L Alvarez-Rosa… - Fluids and Barriers of …, 2022 - Springer
COVID-19, which is caused by Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-
CoV-2), has resulted in devastating morbidity and mortality worldwide due to lethal …

SARS-CoV-2 neuronal invasion and complications: potential mechanisms and therapeutic approaches

O Swain, SK Romano, R Miryala, J Tsai… - Journal of …, 2021 - Soc Neuroscience
Clinical reports suggest that the coronavirus disease-19 (COVID-19) pandemic caused by
severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) has not only taken …

Alteration of the blood-brain barrier by COVID-19 and its implication in the permeation of drugs into the brain

H Hernández-Parra, OD Reyes-Hernández… - Frontiers in Cellular …, 2023 - frontiersin.org
Diverse neurological symptoms have been reported in patients with SARS-CoV-2 disease
(COVID-19), including stroke, ataxia, meningitis, encephalitis, and cognitive impairment …

SARS‐CoV‐2 induces blood‐brain barrier and choroid plexus barrier impairments and vascular inflammation in mice

H Qiao, X Deng, L Qiu, Y Qu, Y Chiu… - Journal of medical …, 2024 - Wiley Online Library
The coronavirus disease of 2019 (COVID‐19) pandemic has led to more than 700 million
confirmed cases and nearly 7 million deaths. Although severe acute respiratory syndrome …

SARS-CoV-2 poorly replicates in cells of the human blood-brain barrier without associated deleterious effects

O Constant, J Barthelemy, K Bollore, E Tuaillon… - Frontiers in …, 2021 - frontiersin.org
Various neurological symptoms have been associated to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection including headache, fever, anosmia, ageusia, but …