L Machlin, AB Miller, J Snyder… - Frontiers in Behavioral …, 2019 - frontiersin.org
Early-life adversity (ELA) is strongly associated with risk for psychopathology. Within adversity, deprivation, and threat may lead to psychopathology through different …
Exposure to early life adversity (ELA) is associated with increased rates of psychopathology and poor physical health. The present study builds on foundational work by Megan Gunnar …
JL Luby, D Barch, D Whalen, R Tillman… - JAMA …, 2017 - jamanetwork.com
Importance Adverse childhood experiences (ACEs) have been associated with poor mental and physical health outcomes. However, the mechanism of this effect, critical to enhancing …
KA McLaughlin - Future work in clinical child and adolescent …, 2018 - taylorfrancis.com
Despite long-standing interest in the influence of adverse early experiences on mental health, systematic scientific inquiry into childhood adversity and developmental outcomes …
Objective Dysregulation of autonomic nervous system and hypothalamic-pituitary-adrenal (HPA) axis function is a putative intermediate phenotype linking childhood adversity (CA) …
Background Recent conceptual models argue that early life adversity (ELA) accelerates development, which may contribute to poor mental and physical health outcomes. Evidence …
Adverse childhood experiences (ACEs) are complex early stressors that may disrupt normal developmental processes in each area of the biopsychosocial model. Specifically, ACEs …
DG Gee - American Journal of Psychiatry, 2021 - Am Psychiatric Assoc
Adversity early in life is common and is a major risk factor for the onset of psychopathology. Delineating the neurodevelopmental pathways by which early adversity affects mental …
Current frameworks for understanding the link between early adverse childhood experiences and later negative life outcomes, including psychopathology, focus on the …