Circulating tumor DNA (ctDNA) is tumor-derived fragmented DNA in the bloodstream that
has come from primary or metastatic cancer sites. Neoplasm-specific genetic and epigenetic …

Assays to detect circulating tumor DNA (ctDNA) have multiple clinically important
applications in management of multiple types of gastrointestinal cancers. Different …

Circulating cell free tumour DNA (ctDNA) maintains the same genomic alterations that are
present in the corresponding tumour, thereby allowing for quantitative and qualitative real …

Colorectal cancer (CRC) is frequently diagnosed at an advanced stage of the disease, the
pathogenesis of which is influenced by genetic and epigenetic events. Circulating tumor …

Cancer cells shed naked DNA molecules into the circulation. This circulating tumor DNA
(ctDNA) has become the predominant analyte for liquid biopsies to understand the …

Tumor biopsy is the standard method for cancer diagnosis and provides an important
sample for pathological assessment. With the development of precision medicine, liquid …

Liquid biopsy is a minimally invasive method for detecting soluble factors, including
circulating tumor DNA (ctDNA), in body fluids. ctDNA carrying tumor-specific genetic or …

Molecular profiling of circulating tumor DNA (ctDNA) is a promising noninvasive tool. Here,
next-generation sequencing (NGS) of blood-derived ctDNA was performed in patients with …

Background Cancer cells release circulating tumor DNA (ctDNA) into the bloodstream,
which can now be quantified and examined using novel high-throughput sequencing …

Circulating tumor DNA (ctDNA) has recently emerged as a minimally invasive “liquid biopsy”
tool in precision medicine. ctDNA-genomic DNA fragments that are released into the …