The engines that drive the complex process of aging are being identified by model-organism
research, thereby providing potential targets and rationale for drug studies. Several studies …

Once a backwater in medical sciences, aging research has emerged and now threatens to
take the forefront. This dramatic change of stature is driven from 3 major events. First and …

Recent discoveries in the science of ageing indicate that lifespan in model organisms such
as yeast, nematodes, flies and mice is plastic and can be manipulated by genetic, nutritional …

Aging is a risk factor for several of the world's most prevalent diseases, including
neurodegenerative disorders, cancer, cardiovascular disease and metabolic disease …

For several decades, understanding ageing and the processes that limit lifespan have
challenged biologists. Thirty years ago, the biology of ageing gained unprecedented …

Human life expectancy in developed countries has increased steadily for over 150 years,
through improvements in public health and lifestyle. More people are hence living long …

Find drugs that delay many diseases of old age Skip to main content Thank you for visiting
nature.com. You are using a browser version with limited support for CSS. To obtain the …

The field of aging is at a precipice. Attention and funding are increasingly focused on this
area, and exciting, fundamentally important findings are being reported literally every day …

The discovery of drugs targeting the fundamental mechanisms of aging (herein called 'aging
drugs') poses a far greater challenge than the discovery of drugs for individual diseases …

Multiple interventions in the aging process have been discovered to extend the healthspan
of model organisms. Both industry and academia are therefore exploring possible …