JK Kresovich, AM Martinez Lopez… - The Journals of …, 2021 - academic.oup.com
Epigenetic age acceleration is considered a measure of biological aging based on genome- wide patterns of DNA methylation. Although age acceleration has been associated with the …
PA Dugué, JK Bassett, JHE Joo… - American journal of …, 2018 - academic.oup.com
Measures of biological age based on blood DNA methylation, referred to as age acceleration (AA), have been developed. We examined whether AA was associated with …
Aging is associated with profound changes in DNA methylation. Recent studies have used DNA methylation to build very accurate age predictors, also named “epigenetic clocks,” that …
Accelerated DNA methylation age is linked to all-cause mortality and environmental factors, but studies of associations with socioeconomic position are limited. Researchers generally …
Background Many DNA methylation-based indicators have been developed as summary measures of epigenetic aging. We examine the associations between 13 epigenetic clocks …
JK Kresovich, EL Garval… - American journal of …, 2021 - academic.oup.com
Epigenetic clocks use DNA methylation to estimate biological age. Whether body composition and physical activity are associated with these clocks is not well understood …
Biomarkers developed from DNA methylation (DNAm) data are of growing interest as predictors of health outcomes and mortality in older populations. However, it is unknown …
Aging involves a diverse set of biological changes accumulating over time that leads to increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify …
DNA methylation (DNAm) algorithms of biological age provide a robust estimate of an individual's chronological age and can predict their risk of age-related disease and mortality …